9FNO
Cryo-EM structure of human CD163 SRCR1-9 in complex with haptoglobin-hemoglobin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Hemopressin | polymer | 142 | 15281.5 | 1 | UniProt (P69905) Pfam (PF00042) | Homo sapiens (human) | |
| 2 | B (B) | Spinorphin | polymer | 147 | 16021.4 | 1 | UniProt (P68871) Pfam (PF00042) | Homo sapiens (human) | |
| 3 | C (C) | Isoform 2 of Haptoglobin alpha chain | polymer | 83 | 9204.2 | 1 | UniProt (P00738) | Homo sapiens (human) | Zonulin, Isoform 2 of Haptoglobin alpha chain |
| 4 | D (D) | Haptoglobin beta chain | polymer | 245 | 27298.0 | 1 | UniProt (P00738) Pfam (PF00089) | Homo sapiens (human) | |
| 5 | E, F, G (E, F, G) | Scavenger receptor cysteine-rich type 1 protein M130 | polymer | 1156 | 125594.8 | 3 | UniProt (Q86VB7) Pfam (PF00530) | Homo sapiens (human) | Hemoglobin scavenger receptor |
| 6 | H, I (A, B) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 2 | Chemie (HEM) | |||
| 7 | J, K, L, O, P... (D, E, F, G) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 12 | Chemie (NAG) | |||
| 8 | M, N, R, V (E, F, G) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 7 |
| Total formula weight | 444589.6 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 4047.8 | |
| All* | Total formula weight | 448637.4 |
