9FL7
Cryo-EM structure of human AK2 bound to reduced human AIFM1 (residues 102-613), class 3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Apoptosis-inducing factor 1, mitochondrial | polymer | 518 | 56516.1 | 2 | UniProt (O95831) Pfam (PF00070) Pfam (PF14721) | Homo sapiens (human) | Programmed cell death protein 8 |
| 2 | C (D) | Adenylate kinase 2, mitochondrial | polymer | 245 | 27147.5 | 1 | UniProt (P54819) Pfam (PF00406) Pfam (PF05191) | Homo sapiens (human) | AK 2,ATP-AMP transphosphorylase 2,ATP:AMP phosphotransferase,Adenylate monophosphate kinase |
| 3 | D, F (A, B) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 2 | Chemie (NAD) | |||
| 4 | E, G (A, B) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 2 | Chemie (FAD) |
Sequence modifications
A, B: 102 - 613 (UniProt: O95831)
D: 1 - 239 (UniProt: P54819)
| PDB | External Database | Details |
|---|---|---|
| Gly 96 | - | expression tag |
| Ile 97 | - | expression tag |
| Asp 98 | - | expression tag |
| Pro 99 | - | expression tag |
| Phe 100 | - | expression tag |
| Thr 101 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -5 | - | expression tag |
| Ile -4 | - | expression tag |
| Asp -3 | - | expression tag |
| Pro -2 | - | expression tag |
| Phe -1 | - | expression tag |
| Thr 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 140179.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 2897.9 | |
| All* | Total formula weight | 143077.7 |
