9FKR
KAT6A IN COMPLEX WITH SMALL MOLECULE INHIBITOR BAY-184
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Histone acetyltransferase KAT6A | polymer | 272 | 32173.2 | 2 | UniProt (Q92794) Pfam (PF17772) Pfam (PF01853) | Homo sapiens (human) | MOZ,YBF2/SAS3,SAS2 and TIP60 protein 3,MYST-3,Monocytic leukemia zinc finger protein,Runt-related transcription factor-binding protein 2,Zinc finger protein 220 |
| 2 | C, F (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D, G (A, B) | 6-(dimethylamino)-~{N}-(2-phenylphenyl)sulfonyl-1-benzofuran-2-carboxamide | non-polymer | 420.5 | 2 | Chemie (A1IDR) | |||
| 4 | E, H (A, B) | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 2 | Chemie (EPE) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 42 | Chemie (HOH) |
Sequence modifications
A, B: 509 - 778 (UniProt: Q92794)
| PDB | External Database | Details |
|---|---|---|
| Gly 507 | - | expression tag |
| Ser 508 | - | expression tag |
| Ser 638 | Cys 638 | engineered mutation |
| Ser 646 | Cys 646 | engineered mutation |
| Ser 723 | Cys 723 | engineered mutation |
| Ser 773 | Cys 773 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 64346.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1448.4 | |
| All* | Total formula weight | 65794.8 |
