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9FHB

Cryo-EM structure of human CD163 SRCR2-4 in complex with haptoglobin-hemoglobin

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Hemoglobin subunit alphapolymer14215281.51UniProt (P69905)
Pfam (PF00042)
Homo sapiens (human)Alpha-globin,Hemoglobin alpha chain
2B
(B)
Hemoglobin subunit betapolymer14716021.41UniProt (P68871)
Pfam (PF00042)
Homo sapiens (human)Beta-globin,Hemoglobin beta chain
3C
(C)
Haptoglobinpolymer40645262.21UniProt (P00738)
Pfam (PF00089)
Homo sapiens (human)Zonulin,Haptoglobin isoform 2
4D
(D)
Scavenger receptor cysteine-rich type 1 protein M130polymer1156125594.81UniProt (Q86VB7)
Pfam (PF00530)
Homo sapiens (human)Hemoglobin scavenger receptor,CD163
5E, F
(A, B)
PROTOPORPHYRIN IX CONTAINING FEnon-polymer616.52Chemie (HEM)
6G, H, K
(C, D)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.23Chemie (NAG)
7I, J
(D)
CALCIUM IONnon-polymer40.12Chemie (CA)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight202159.9
Non-Polymers*Number of molecules7
Total formula weight1976.8
All*Total formula weight204136.7
*Water molecules are not included.

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PDB entries from 2025-06-11

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