9F6J
Human DNA Polymerase epsilon bound to T-C mismatched DNA (Polymerase Arrest state)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | DNA polymerase epsilon catalytic subunit A | polymer | 1200 | 138137.6 | 1 | UniProt (Q07864) Pfam (PF03104) Pfam (PF22634) In PDB | Homo sapiens (human) | 3'-5' exodeoxyribonuclease,DNA polymerase II subunit A |
| 2 | P | DNA nascent strand | polymer | 31 | 9489.1 | 1 | Homo sapiens | ||
| 3 | T | DNA template strand | polymer | 31 | 9458.1 | 1 | Homo sapiens | ||
| 4 | A | IRON/SULFUR CLUSTER | non-polymer | 351.6 | 1 | Chemie (SF4) |
Sequence modifications
A: 1 - 1200 (UniProt: Q07864)
| PDB | External Database | Details |
|---|---|---|
| Ala 275 | Asp 275 | engineered mutation |
| Ala 277 | Glu 277 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 157084.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 351.6 | |
| All* | Total formula weight | 157436.4 |
