9F6G

Human USP30 chimera bound to Ubiquitin-PA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Ubiquitin carboxyl-terminal hydrolase 30,Ubiquitin carboxyl-terminal hydrolase 14,Ubiquitin carboxyl-terminal hydrolase 35	polymer	317	36126.7	1	UniProt (Q70CQ3) UniProt (P54578) UniProt (Q9P2H5) Pfam (PF00443)	Homo sapiens (human)	Deubiquitinating enzyme 30,Ubiquitin thioesterase 30,Ubiquitin-specific-processing protease 30,Ub-specific protease 30,Deubiquitinating enzyme 14,Ubiquitin thioesterase 14,Ubiquitin-specific-processing protease 14,Deubiquitinating enzyme 35,Ubiquitin thioesterase 35,Ubiquitin-specific-processing protease 35
2	B (B)	Polyubiquitin-B	polymer	75	8519.8	1	UniProt (P0CG47) Pfam (PF00240) UniProt (by SIFTS) (P0CG48)	Homo sapiens (human)
3	C (A)	prop-2-en-1-amine	non-polymer		57.1	1	Chemie (AYE)
4	D, E (A, B)	water	water		18.0	355	Chemie (HOH)

Sequence modifications

A: 64 - 212 (UniProt: Q70CQ3)

PDB	External Database	Details
Gly 62	-	expression tag
Pro 63	-	expression tag

A: 217 - 224 (UniProt: Q70CQ3)

A: 225 - 249 (UniProt: P54578)
A: 250 - 275 (UniProt: Q70CQ3)
A: 276 - 301 (UniProt: P54578)
A: 318 - 348 (UniProt: Q70CQ3)

PDB	External Database	Details
Asp 348	Phe 348	engineered mutation

A: 349 - 361 (UniProt: Q9P2H5)
A: 437 - 502 (UniProt: Q70CQ3)

Sequence viewer

Contents of the asymmetric unit

*Water molecules are not included.