9F6C
Cardiac myosin motor domain in the pre-powerstroke state co-crystallized with the inhibitor aficamten
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Myosin-7 | polymer | 782 | 89315.1 | 2 | UniProt (Q9BE39) Pfam (PF02736) Pfam (PF00063) | Bos taurus (cattle) | Myosin heavy chain 7,Myosin heavy chain slow isoform,MyHC-slow,Myosin heavy chain,cardiac muscle beta isoform,MyHC-beta |
| 2 | C (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 3 | D, H (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | E, I (A, B) | aficamten | non-polymer | 337.4 | 2 | Chemie (6I6) | |||
| 5 | F, J (A, B) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 2 | Chemie (ADP) | |||
| 6 | G, K (A, B) | VANADATE ION | non-polymer | 114.9 | 2 | Chemie (VO4) | |||
| 7 | L, M (A, B) | water | water | 18.0 | 330 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 178630.3 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1903.7 | |
| All* | Total formula weight | 180534.0 |
