9F6B
Human neuropilin-1 in a complex with a quinoline based antagonists
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Neuropilin-1 | polymer | 158 | 17917.3 | 2 | UniProt (O14786) Pfam (PF00754) | Homo sapiens (human) | Vascular endothelial cell growth factor 165 receptor |
| 2 | C, D (A, B) | (2~{S})-2-[[3-[[6-[3-(aminomethyl)phenyl]quinolin-8-yl]sulfonylamino]thiophen-2-yl]carbonylamino]-5-carbamimidamido-pentanoic acid | non-polymer | 595.7 | 2 | Chemie (A1IAT) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 460 | Chemie (HOH) |
Sequence modifications
A, B: 273 - 427 (UniProt: O14786)
| PDB | External Database | Details |
|---|---|---|
| Gly 270 | - | expression tag |
| His 271 | - | expression tag |
| Met 272 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 35834.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1191.4 | |
| All* | Total formula weight | 37026.0 |
