9F43

cryo-EM structure of human LST2 bound to human mTOR complex 1, focused on RAPTOR

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	E	Regulatory-associated protein of mTOR	polymer	1363	152764.7	1	UniProt (Q8N122) Pfam (PF14538) Pfam (PF02985) Pfam (PF00400) In PDB	Homo sapiens (human)	Raptor,p150 target of rapamycin (TOR)-scaffold protein
2	G	Lateral signaling target protein 2 homolog	polymer	887	96604.5	1	UniProt (Q9HCC9) Pfam (PF01363) In PDB	Homo sapiens (human)	hLst2,Zinc finger FYVE domain-containing protein 28

Sequence modifications

E: 1 - 1335 (UniProt: Q8N122)

PDB	External Database	Details
His -27	-	expression tag
His -26	-	expression tag
His -25	-	expression tag
His -24	-	expression tag
His -23	-	expression tag
His -22	-	expression tag
His -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
Glu -17	-	expression tag
Gln -16	-	expression tag
Lys -15	-	expression tag
Leu -14	-	expression tag
Ile -13	-	expression tag
Ser -12	-	expression tag
Glu -11	-	expression tag
Glu -10	-	expression tag
Asp -9	-	expression tag
Leu -8	-	expression tag
Asp -7	-	expression tag
Tyr -6	-	expression tag
Lys -5	-	expression tag
Asp -4	-	expression tag
Asp -3	-	expression tag
Asp -2	-	expression tag
Asp -1	-	expression tag
Lys 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	249369.1
All*	Total formula weight	249369.1

*Water molecules are not included.