9F3V

RIP2K kinase domain dimer with bound compound 37 (N399), a speific NOD1 pathway inhibitor

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Receptor-interacting serine/threonine-protein kinase 2	polymer	320	36644.2	2	UniProt (O43353) Pfam (PF07714)	Homo sapiens (human)	CARD-containing interleukin-1 beta-converting enzyme-associated kinase,CARD-containing IL-1 beta ICE-kinase,RIP-like-interacting CLARP kinase,Receptor-interacting protein 2,RIP-2,Tyrosine-protein kinase RIPK2
2	C, D (A, B)	N-[2,4-bis(chloranyl)-5-methoxy-phenyl]-7-[2-(diethylamino)ethoxy]-6-methoxy-quinazolin-4-amine	non-polymer		465.4	2	Chemie (A1H90)
3	E, F (A, B)	water	water		18.0	129	Chemie (HOH)

Sequence modifications

A, B: 1 - 316 (UniProt: O43353)

PDB	External Database	Details
Gly -3	-	expression tag
Ala -2	-	expression tag
Met -1	-	expression tag
Ala 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	73288.3
Non-Polymers*	Number of molecules	2
	Total formula weight	930.7
All*	Total formula weight	74219.1

*Water molecules are not included.