9F1I
Crystal structure of a first-in-class antibody for alpha-1,6-fucosylated prostate-specific antigen, target bound
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (H, I) | Heavy chain rabbit fab | polymer | 230 | 23734.5 | 2 | Oryctolagus cuniculus | ||
| 2 | C, D (L, M) | Light chain rabbit fab | polymer | 217 | 22957.4 | 2 | Oryctolagus cuniculus | ||
| 3 | E, F (P, Q) | Prostate specific antigen | polymer | 10 | 1114.4 | 2 | UniProt (Q8NCW4) UniProt (by SIFTS) (P07288) | Homo sapiens | |
| 4 | G, H (A, C) | alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 367.3 | 2 | In PDB GlyTouCan (G86851RC) | |||
| 5 | I, J, K, L, M... (H, I, L, M) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
| 6 | O, P (P, Q) | 2-[2-(2-azanylethoxy)ethoxy]ethanoic acid | non-polymer | 163.2 | 2 | Chemie (PFX) PubChem (362706) | |||
| 7 | Q, R, S, T, U... (H, I, L, M, P...) | water | water | 18.0 | 795 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 95612.6 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 734.7 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 698.8 | |
| All* | Total formula weight | 97046.0 |
