9F16
Structure of a homomeric LRRC8C point mutation disease mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Volume-regulated anion channel subunit LRRC8C | polymer | 811 | 93362.3 | 7 | UniProt (Q8TDW0) Pfam (PF12534) Pfam (PF13855) | Homo sapiens (human) | Factor for adipocyte differentiation 158,Leucine-rich repeat-containing protein 8C |
Sequence modifications
A, B, C, D, E, F, G: 2 - 801 (UniProt: Q8TDW0)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
| Ser 1 | - | expression tag |
| Gly 205 | Asp 205 | conflict |
| Leu 390 | Val 390 | engineered mutation |
| Ala 802 | - | expression tag |
| Asp 803 | - | expression tag |
| Ala 804 | - | expression tag |
| Leu 805 | - | expression tag |
| Glu 806 | - | expression tag |
| Val 807 | - | expression tag |
| Leu 808 | - | expression tag |
| Phe 809 | - | expression tag |
| Gln 810 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 7 |
| Total formula weight | 653536.1 | |
| All* | Total formula weight | 653536.1 |
