9F07
TUBULIN:STATHMIN:DARPIN:TAU MTBR3 COMPLEX
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E (A, E) | Tubulin alpha chain | polymer | 451 | 50204.4 | 2 | UniProt (D0VWZ0) | Ovis aries (sheep) | |
| 2 | B, F (B, F) | Tubulin beta chain | polymer | 445 | 49999.9 | 2 | UniProt (D0VWY9) | Ovis aries (sheep) | |
| 3 | C, G (C, G) | Stathmin-4 | polymer | 121 | 13157.8 | 2 | UniProt (Q9H169) Pfam (PF00836) | Homo sapiens (human) | Stathmin-like protein B3,RB3,SLD1-R3 |
| 4 | D, H (D, H) | D2-R3 | polymer | 190 | 19666.9 | 2 | synthetic construct | ||
| 5 | I, U (A, E) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 2 | Chemie (GTP) PubChem (177679032) PubChem (135400627) PubChem (135487750) PubChem (136088935) PubChem (136803486) PubChem (135398633) PubChem (135544356) PubChem (135547949) PubChem (135600366) PubChem (135749822) PubChem (136005188) PubChem (136073923) PubChem (136240914) PubChem (136664747) PubChem (136772743) PubChem (136772744) PubChem (136803487) PubChem (137286749) PubChem (164715984) PubChem (171699466) | |||
| 6 | J, V (A, E) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) PubChem (888) | |||
| 7 | K, W (B, F) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 2 | Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537) | |||
| 8 | L, M, N, O, X... (B, F) | GLYCEROL | non-polymer | 92.1 | 7 | Chemie (GOL) PubChem (753) | |||
| 9 | CA, P (F, B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) PubChem (8117) | |||
| 10 | Q (B) | PENTAETHYLENE GLYCOL | non-polymer | 238.3 | 1 | Chemie (1PE) PubChem (62551) | |||
| 11 | R (B) | HEXAETHYLENE GLYCOL | non-polymer | 282.3 | 1 | Chemie (P6G) PubChem (17472) | |||
| 12 | AA, BA, DA, S, T (F, H, B, D) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 5 | Chemie (PGE) | |||
| 13 | EA, FA, GA, HA, IA... (A, B, C, D, E...) | water | water | 18.0 | 328 | Chemie (HOH) |
Sequence modifications
A, E: 1 - 451 (UniProt: D0VWZ0)
B, F: 1 - 455 (UniProt: D0VWY9)
C, G: 206 - 263 (UniProt: Q9H169)
C, G: 264 - 291 (UniProt: Q9H169)
| PDB | External Database | Details |
|---|---|---|
| Ser 232 | Gly 232 | conflict |
| Ser 340 | Thr 340 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Cys 203 | Ser 201 | conflict |
| Ile 318 | Val 316 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Met 204 | - | initiating methionine |
| Ala 205 | - | expression tag |
| Ala 215 | Cys 58 | engineered mutation |
| Trp 221 | Phe 64 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Phe 266 | Leu 160 | engineered mutation |
| Gly 292 | - | expression tag |
| Gly 293 | - | expression tag |
| Gly 294 | - | expression tag |
| Gly 295 | - | expression tag |
| Ser 296 | - | expression tag |
| Gly 297 | - | expression tag |
| Gly 298 | - | expression tag |
| Gly 299 | - | expression tag |
| Gly 300 | - | expression tag |
| Ser 301 | - | expression tag |
| Gly 302 | - | expression tag |
| Gly 303 | - | expression tag |
| Gly 304 | - | expression tag |
| Ser 305 | - | expression tag |
| Val 306 | - | expression tag |
| Gln 307 | - | expression tag |
| Ile 308 | - | expression tag |
| Val 309 | - | expression tag |
| Tyr 310 | - | expression tag |
| Lys 311 | - | expression tag |
| Pro 312 | - | expression tag |
| Val 313 | - | expression tag |
| Asp 314 | - | expression tag |
| Leu 315 | - | expression tag |
| Ser 316 | - | expression tag |
| Lys 317 | - | expression tag |
| Val 318 | - | expression tag |
| Thr 319 | - | expression tag |
| Ser 320 | - | expression tag |
| Lys 321 | - | expression tag |
| Ser 322 | - | expression tag |
| Gly 323 | - | expression tag |
| Ser 324 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 266058.2 | |
| Non-Polymers* | Number of molecules | 22 |
| Total formula weight | 4109.7 | |
| All* | Total formula weight | 270167.9 |
