9EZJ
Apo human TDO in complex with a bound inhibitor (Cpd-4)
This is a non-PDB format compatible entry.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Tryptophan 2,3-dioxygenase | polymer | 403 | 47747.1 | 4 | UniProt (P48775) Pfam (PF03301) In PDB | Homo sapiens (human) | TDO,Tryptamin 2,3-dioxygenase,Tryptophan oxygenase,TO,TRPO,Tryptophan pyrrolase,Tryptophanase |
2 | A, B, C, D | alpha-methyl-L-tryptophan | non-polymer | 218.3 | 4 | Chemie (ZIQ) | |||
3 | A, B, C, D | ethyl (9~{R})-2-methoxy-4-oxidanylidene-9-[[(1~{S})-1-phenylethyl]-[(2-propan-2-ylphenyl)carbamoyl]amino]-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidine-3-carboxylate | non-polymer | 532.6 | 4 | Chemie (A1H8G) | |||
4 | water | water | 18.0 | 8 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 19 - 406 (UniProt: P48775)
PDB | External Database | Details |
---|---|---|
Met 4 | - | initiating methionine |
Arg 5 | - | expression tag |
Gly 6 | - | expression tag |
Ser 7 | - | expression tag |
His 8 | - | expression tag |
His 9 | - | expression tag |
His 10 | - | expression tag |
His 11 | - | expression tag |
His 12 | - | expression tag |
His 13 | - | expression tag |
Gly 14 | - | expression tag |
Ile 15 | - | expression tag |
Asp 16 | - | expression tag |
His 17 | - | expression tag |
Met 18 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 190988.5 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 3003.5 | |
All* | Total formula weight | 193992.0 |