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9EYV

Human PRMT5 in complex with AZ compound 12

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AProtein arginine N-methyltransferase 5, N-terminally processedpolymer63772766.71UniProt (O14744)
In PDB
Homo sapiens (human)
2BMethylosome protein WDR77polymer34236757.21UniProt (Q9BQA1)
In PDB
Homo sapiens (human)Androgen receptor cofactor p44,Methylosome protein 50,MEP-50,WD repeat-containing protein 77,p44/Mep50
3A(1~{S})-~{N}-[(4-fluorophenyl)methyl]-3-oxidanylidene-2-(1~{H}-pyrrolo[3,2-b]pyridin-2-ylmethyl)-1~{H}-isoindole-1-carboxamidenon-polymer414.41Chemie (A1H76)
4A5'-DEOXY-5'-METHYLTHIOADENOSINEnon-polymer297.31Chemie (MTA)
5ASULFATE IONnon-polymer96.11Chemie (SO4)
6waterwater18.070Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight109523.9
Non-Polymers*Number of molecules3
Total formula weight807.8
All*Total formula weight110331.7
*Water molecules are not included.

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PDB entries from 2024-08-14

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