9EWG
DNA Polymerase Lambda I493K, TTP:At Ca2+ Ground State Ternary Complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA polymerase lambda | polymer | 330 | 36809.1 | 1 | UniProt (Q9UGP5) Pfam (PF14716) Pfam (PF10391) Pfam (PF14792) Pfam (PF14791) | Homo sapiens (human) | Pol Lambda,DNA polymerase beta-2,Pol beta2,DNA polymerase kappa |
| 2 | B (D) | DNA primer strand downstream | polymer | 4 | 1191.8 | 1 | Homo sapiens | ||
| 3 | C (P) | DNA primer strand upstream | polymer | 6 | 1793.2 | 1 | Homo sapiens | ||
| 4 | D (T) | DNA template strand | polymer | 11 | 3374.2 | 1 | Homo sapiens | ||
| 5 | E, F, G (A) | SODIUM ION | non-polymer | 23.0 | 3 | Chemie (NA) PubChem (923) | |||
| 6 | H, I, J, L (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 7 | K, N (A, D) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) PubChem (271) | |||
| 8 | M (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) PubChem (753) | |||
| 9 | O (P) | THYMIDINE-5'-PHOSPHATE | non-polymer | 322.2 | 1 | Chemie (TMP) PubChem (18531120) PubChem (20711568) PubChem (1139) PubChem (23657880) PubChem (24802545) PubChem (44361457) PubChem (25113134) PubChem (51397487) PubChem (444919) PubChem (9700) PubChem (5274091) PubChem (5748250) PubChem (10147784) PubChem (129069890) PubChem (133126478) PubChem (164603144) | |||
| 10 | P, Q, R, S (A, D, P, T) | water | water | 18.0 | 248 | Chemie (HOH) |
Sequence modifications
A: 242 - 462 (UniProt: Q9UGP5)
A: 472 - 575 (UniProt: Q9UGP5)
| PDB | External Database | Details |
|---|---|---|
| Gly 241 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Lys 463 | - | linker |
| Gly 464 | - | linker |
| Glu 470 | - | linker |
| Thr 471 | - | linker |
| Lys 492 | Ile 492 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 43168.4 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 811.7 | |
| All* | Total formula weight | 43980.1 |
