9EWG
DNA Polymerase Lambda I493K, TTP:At Ca2+ Ground State Ternary Complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA polymerase lambda | polymer | 330 | 36809.1 | 1 | UniProt (Q9UGP5) Pfam (PF14716) Pfam (PF10391) Pfam (PF14792) Pfam (PF14791) | Homo sapiens (human) | Pol Lambda,DNA polymerase beta-2,Pol beta2,DNA polymerase kappa |
| 2 | B (D) | DNA primer strand downstream | polymer | 4 | 1191.8 | 1 | Homo sapiens | ||
| 3 | C (P) | DNA primer strand upstream | polymer | 6 | 1793.2 | 1 | Homo sapiens | ||
| 4 | D (T) | DNA template strand | polymer | 11 | 3374.2 | 1 | Homo sapiens | ||
| 5 | E, F, G (A) | SODIUM ION | non-polymer | 23.0 | 3 | Chemie (NA) | |||
| 6 | H, I, J, L (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 7 | K, N (A, D) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 8 | M (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 9 | O (P) | THYMIDINE-5'-PHOSPHATE | non-polymer | 322.2 | 1 | Chemie (TMP) | |||
| 10 | P, Q, R, S (A, D, P, T) | water | water | 18.0 | 248 | Chemie (HOH) |
Sequence modifications
A: 242 - 462 (UniProt: Q9UGP5)
A: 472 - 575 (UniProt: Q9UGP5)
| PDB | External Database | Details |
|---|---|---|
| Gly 241 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Lys 463 | - | linker |
| Gly 464 | - | linker |
| Glu 470 | - | linker |
| Thr 471 | - | linker |
| Lys 492 | Ile 492 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 43168.4 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 811.7 | |
| All* | Total formula weight | 43980.1 |
