9EWB
DNA Polymerase Lambda I493R, TTP:At Ca2+ Ground State Ternary Complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA polymerase lambda | polymer | 330 | 36805.1 | 1 | UniProt (Q9UGP5) Pfam (PF14716) Pfam (PF10391) Pfam (PF14792) Pfam (PF14791) | Homo sapiens (human) | Pol Lambda,DNA polymerase beta-2,Pol beta2,DNA polymerase kappa |
| 2 | B (F) | DNA (5'-D(*CP*GP*GP*CP*AP*GP*TP*AP*CP*TP*G)-3') | polymer | 11 | 3374.2 | 1 | Homo sapiens | ||
| 3 | C (G) | DNA (5'-D(*CP*AP*GP*TP*AP*C)-3') | polymer | 6 | 1793.2 | 1 | Homo sapiens | ||
| 4 | D (H) | DNA (5'-D(P*GP*CP*CP*G)-3') | polymer | 4 | 1191.8 | 1 | Homo sapiens | ||
| 5 | E (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 6 | F, G (A) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 7 | H (A) | THYMIDINE-5'-TRIPHOSPHATE | non-polymer | 482.2 | 1 | Chemie (TTP) | |||
| 8 | I, J, K, L, M... (A, F) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 7 | Chemie (EDO) | |||
| 9 | P, Q, R, S (A, F, G, H) | water | water | 18.0 | 300 | Chemie (HOH) |
Sequence modifications
A: 242 - 462 (UniProt: Q9UGP5)
A: 467 - 570 (UniProt: Q9UGP5)
| PDB | External Database | Details |
|---|---|---|
| Gly 241 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Lys 463 | - | linker |
| Gly 464 | - | linker |
| Glu 465 | - | linker |
| Thr 466 | - | linker |
| Arg 487 | Ile 492 | engineered mutation |
| Ala 538 | Cys 543 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 43164.3 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1002.7 | |
| All* | Total formula weight | 44167.0 |
