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9EVJ

Crystal Structure of human Collagen Hydroxylysine Galactosyltransferase GLT25D1/COLGALT1: complex with Mn2+ and UDP-Gal

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Procollagen galactosyltransferase 1polymer59468589.22UniProt (Q8NBJ5)
Pfam (PF13704)
Pfam (PF01755)
Homo sapiens (human)Collagen beta(1-O)galactosyltransferase 1,ColGalT 1,Glycosyltransferase 25 family member 1,Hydroxylysine galactosyltransferase 1
2C, L
(A, B)
GALACTOSE-URIDINE-5'-DIPHOSPHATEnon-polymer566.32Chemie (GDU)
3D
(A)
URIDINE-5'-DIPHOSPHATEnon-polymer404.21Chemie (UDP)
4E
(A)
MANGANESE (II) IONnon-polymer54.91Chemie (MN)
5F, G
(A)
2-(N-MORPHOLINO)-ETHANESULFONIC ACIDnon-polymer195.22Chemie (MES)
6H, I, J, M, N...
(A, B)
CHLORIDE IONnon-polymer35.56Chemie (CL)
7K, Q
(A, B)
CALCIUM IONnon-polymer40.12Chemie (CA)
8P
(B)
SODIUM IONnon-polymer23.01Chemie (NA)
9R, S
(A, B)
waterwater18.0136Chemie (HOH)
Sequence modifications
A, B: 30 - 618 (UniProt: Q8NBJ5)
PDBExternal DatabaseDetails
Gly 28-expression tag
Ser 29-expression tag
Ala 619-expression tag
Ala 620-expression tag
Ala 621-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight137178.3
Non-Polymers*Number of molecules15
Total formula weight2298.0
All*Total formula weight139476.4
*Water molecules are not included.

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PDB entries from 2025-06-18

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