9ESI
Structure of a B-state intermediate committed to discard (Bd-II state)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (e) | Stress response protein bis1 | polymer | 384 | 43084.0 | 1 | UniProt (O59793) Pfam (PF09751) | Schizosaccharomyces pombe (fission yeast) | Splicing factor ESS-2 homolog |
| 2 | B (p) | Protein saf4 | polymer | 299 | 34751.5 | 1 | UniProt (O60141) Pfam (PF04502) | Schizosaccharomyces pombe (fission yeast) | |
| 3 | C (2) | U2snRNA | polymer | 186 | 59207.5 | 1 | GenBank (5081) | Schizosaccharomyces pombe (fission yeast) | |
| 4 | D (5) | U5snRNA | polymer | 120 | 38191.4 | 1 | GenBank (5125) | Schizosaccharomyces pombe (fission yeast) | |
| 5 | E (A) | Pre-mRNA-splicing factor spp42 | polymer | 2363 | 274917.8 | 1 | UniProt (O14187) Pfam (PF08082) Pfam (PF08083) Pfam (PF10598) Pfam (PF10597) Pfam (PF10596) Pfam (PF12134) Pfam (PF01398) Pfam (PF08084) | Schizosaccharomyces pombe (fission yeast) | Complexed with cdc5 protein 6 |
| 6 | F (B) | Pre-mRNA-splicing factor cwf10 | polymer | 984 | 111445.3 | 1 | UniProt (O94316) Pfam (PF00009) Pfam (PF03144) Pfam (PF03764) Pfam (PF00679) Pfam (PF16004) | Schizosaccharomyces pombe (fission yeast) | 114 kDa U5 small nuclear ribonucleoprotein component homolog,Complexed with cdc5 protein 10 |
| 7 | G (C) | Pre-mRNA-splicing factor cwf17 | polymer | 340 | 37477.2 | 1 | UniProt (O94620) Pfam (PF00400) | Schizosaccharomyces pombe (fission yeast) | Complexed with cdc5 protein 17 |
| 8 | H (D) | Small nuclear ribonucleoprotein Sm D3 | polymer | 97 | 11050.9 | 1 | UniProt (Q9UUC6) Pfam (PF01423) | Schizosaccharomyces pombe (fission yeast) | Sm-D3,snRNP core protein D3 |
| 9 | I (E) | Small nuclear ribonucleoprotein-associated protein B | polymer | 147 | 15493.0 | 1 | UniProt (Q10163) Pfam (PF01423) | Schizosaccharomyces pombe (fission yeast) | snRNP-B,Sm protein B,Sm-B,SmB |
| 10 | J (F) | Small nuclear ribonucleoprotein Sm D1 | polymer | 117 | 13115.4 | 1 | UniProt (O42661) Pfam (PF01423) | Schizosaccharomyces pombe (fission yeast) | Sm-D1,snRNP core protein D1 |
| 11 | K (G) | Small nuclear ribonucleoprotein Sm D2 | polymer | 115 | 13119.3 | 1 | UniProt (O14036) Pfam (PF01423) | Schizosaccharomyces pombe (fission yeast) | Sm-D2,Complexed with cdc5 protein 9,snRNP core protein D2 |
| 12 | L (H) | Small nuclear ribonucleoprotein E | polymer | 84 | 9702.4 | 1 | UniProt (Q9USZ3) Pfam (PF01423) | Schizosaccharomyces pombe (fission yeast) | snRNP-E,Sm protein E,Sm-E,SmE |
| 13 | M (I) | Small nuclear ribonucleoprotein F | polymer | 78 | 8667.1 | 1 | UniProt (O59734) Pfam (PF01423) | Schizosaccharomyces pombe (fission yeast) | snRNP-F,Sm protein F,Sm-F,SmF |
| 14 | N (J) | Small nuclear ribonucleoprotein G | polymer | 77 | 8616.0 | 1 | UniProt (O74966) Pfam (PF01423) | Schizosaccharomyces pombe (fission yeast) | snRNP-G,Sm protein G,Sm-G,SmG |
| 15 | O (K) | Pre-mRNA-splicing factor prp5 | polymer | 473 | 52492.1 | 1 | UniProt (O13615) Pfam (PF00400) | Schizosaccharomyces pombe (fission yeast) | Complexed with cdc5 protein 1,Pre-mRNA-processing protein 5 |
| 16 | P (L) | Pre-mRNA-processing protein 45 | polymer | 557 | 62798.2 | 1 | UniProt (Q09882) Pfam (PF02731) | Schizosaccharomyces pombe (fission yeast) | Complexed with cdc5 protein 13,Transcriptional coregulator snw1 |
| 17 | Q (M) | Pre-mRNA-splicing factor cwf5 | polymer | 354 | 39640.4 | 1 | UniProt (O59800) Pfam (PF21369) Pfam (PF00076) | Schizosaccharomyces pombe (fission yeast) | Complexed with cdc5 protein 5 |
| 18 | R (N) | Pre-mRNA-splicing factor cwf11 | polymer | 1284 | 148532.9 | 1 | UniProt (O94508) Pfam (PF16399) Pfam (PF13087) | Schizosaccharomyces pombe (fission yeast) | Complexed with cdc5 protein 11 |
| 19 | S (O) | Pre-mRNA-splicing factor cwf14 | polymer | 146 | 17122.8 | 1 | UniProt (O74772) Pfam (PF01125) | Schizosaccharomyces pombe (fission yeast) | Complexed with cdc5 protein 14 |
| 20 | T (P) | Pre-mRNA-splicing factor cwf2 | polymer | 388 | 44343.1 | 1 | UniProt (P87126) Pfam (PF16131) Pfam (PF00076) | Schizosaccharomyces pombe (fission yeast) | Complexed with cdc5 protein 2,Pre-mRNA-processing protein 3 |
| 21 | U (Q) | Pre-mRNA-splicing factor cwf15 | polymer | 265 | 30479.0 | 1 | UniProt (P78794) Pfam (PF04889) | Schizosaccharomyces pombe (fission yeast) | Complexed with cdc5 protein 15 |
| 22 | V (R) | Pre-mRNA-splicing factor cwf4 | polymer | 674 | 80964.8 | 1 | UniProt (P87312) Pfam (PF05843) Pfam (PF02184) | Schizosaccharomyces pombe (fission yeast) | Complexed with cdc5 protein 4 |
| 23 | W, X, Y, Z (S, T, U, V) | Pre-mRNA-processing factor 19 | polymer | 488 | 54244.0 | 4 | UniProt (O14011) Pfam (PF08606) Pfam (PF00400) | Schizosaccharomyces pombe (fission yeast) | Complexed with cdc5 protein 8,RING-type E3 ubiquitin transferase PRP19 |
| 24 | AA (W) | Pre-mRNA-splicing factor cdc5 | polymer | 757 | 86981.3 | 1 | UniProt (P39964) Pfam (PF00249) Pfam (PF11831) | Schizosaccharomyces pombe (fission yeast) | Cell division control protein 5 |
| 25 | BA (X) | Pre-mRNA-splicing factor cwf3 | polymer | 790 | 92759.9 | 1 | UniProt (Q9P7R9) Pfam (PF05843) | Schizosaccharomyces pombe (fission yeast) | Complexed with cdc5 protein 3 |
| 26 | CA (Y) | Pre-mRNA-splicing factor syf2 | polymer | 229 | 28037.5 | 1 | UniProt (O59733) Pfam (PF08231) | Schizosaccharomyces pombe (fission yeast) | |
| 27 | DA (Z) | Pre-mRNA-splicing factor cwf7 | polymer | 187 | 21348.2 | 1 | UniProt (Q9USV3) Pfam (PF05700) | Schizosaccharomyces pombe (fission yeast) | Complexed with cdc5 protein 7,Splicing factor 27 |
| 28 | EA (a) | Pre-mRNA-processing factor 17 | polymer | 558 | 63211.3 | 1 | UniProt (O43071) Pfam (PF00400) | Schizosaccharomyces pombe (fission yeast) | |
| 29 | FA (b) | Pre-mRNA-splicing factor cwf21 | polymer | 293 | 34617.8 | 1 | UniProt (O14161) Pfam (PF08312) | Schizosaccharomyces pombe (fission yeast) | Complexed with cdc5 protein 21 |
| 30 | GA (c) | Pre-mRNA-splicing factor cwf22 | polymer | 887 | 102928.4 | 1 | UniProt (Q9P6R9) Pfam (PF02854) Pfam (PF02847) | Schizosaccharomyces pombe (fission yeast) | Complexed with cdc5 protein 22 |
| 31 | HA (d) | Peptidyl-prolyl cis-trans isomerase ppi1 | polymer | 155 | 16884.2 | 1 | UniProt (P87051) Pfam (PF00160) | Schizosaccharomyces pombe (fission yeast) | PPIase ppi1,Cyclophilin ppi1,Rotamase ppi1 |
| 32 | IA (m) | G-patch domain-containing protein C1486.03 | polymer | 797 | 91791.2 | 1 | UniProt (Q9UTK6) Pfam (PF01585) Pfam (PF07842) | Schizosaccharomyces pombe (fission yeast) | |
| 33 | JA (n) | Uncharacterized protein C17A2.08c | polymer | 361 | 41937.6 | 1 | UniProt (O13758) Pfam (PF15458) | Schizosaccharomyces pombe (fission yeast) | |
| 34 | KA (y) | Uncharacterized protein C20H4.06c | polymer | 534 | 60850.1 | 1 | UniProt (Q9HE07) Pfam (PF07713) | Schizosaccharomyces pombe (fission yeast) | |
| 35 | LA (z) | Putative pre-mRNA-splicing factor ATP-dependent RNA helicase C20H4.09 | polymer | 647 | 73113.7 | 1 | UniProt (Q9HE06) Pfam (PF00270) Pfam (PF00271) Pfam (PF04408) Pfam (PF21010) Pfam (PF07717) | Schizosaccharomyces pombe (fission yeast) | DEAH-box helicase C20H4.09 |
| 36 | MA (r) | UNK1 | polymer | 346 | 29464.2 | 1 | Schizosaccharomyces pombe (fission yeast) | ||
| 37 | NA (q) | UNK2 | polymer | 56 | 4933.0 | 1 | Schizosaccharomyces pombe (fission yeast) | ||
| 38 | OA (6) | U6snRNA | polymer | 99 | 31864.0 | 1 | GenBank (891582601) | Schizosaccharomyces pombe (fission yeast) | |
| 39 | PA (1) | pre-mRNA | polymer | 29 | 9135.3 | 1 | Schizosaccharomyces pombe (fission yeast) | ||
| 40 | QA (f) | UNK3 | polymer | 22 | 1890.3 | 1 | Schizosaccharomyces pombe (fission yeast) | ||
| 41 | RA (A) | INOSITOL HEXAKISPHOSPHATE | non-polymer | 660.0 | 1 | Chemie (IHP) | |||
| 42 | SA (B) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 1 | Chemie (GTP) | |||
| 43 | AB, BB, DB, TA (6, B) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 44 | UA, VA, WA, XA, YA... (M, O, P) | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) | |||
| 45 | CB (6) | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 43 |
| Total formula weight | 2163935.9 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 1712.0 | |
| All* | Total formula weight | 2165647.9 |
