9ESI

Structure of a B-state intermediate committed to discard (Bd-II state)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000244	biological_process	spliceosomal tri-snRNP complex assembly
A	0000393	biological_process	spliceosomal conformational changes to generate catalytic conformation
A	0000398	biological_process	mRNA splicing, via spliceosome
A	0000974	cellular_component	Prp19 complex
A	0003723	molecular_function	RNA binding
A	0004843	molecular_function	cysteine-type deubiquitinase activity
A	0005634	cellular_component	nucleus
A	0005681	cellular_component	spliceosomal complex
A	0005682	cellular_component	U5 snRNP
A	0006397	biological_process	mRNA processing
A	0008233	molecular_function	peptidase activity
A	0008237	molecular_function	metallopeptidase activity
A	0008380	biological_process	RNA splicing
A	0017070	molecular_function	U6 snRNA binding
A	0030619	molecular_function	U1 snRNA binding
A	0030620	molecular_function	U2 snRNA binding
A	0030623	molecular_function	U5 snRNA binding
A	0045292	biological_process	mRNA cis splicing, via spliceosome
A	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
A	0071013	cellular_component	catalytic step 2 spliceosome
A	0071014	cellular_component	post-mRNA release spliceosomal complex
A	0097157	molecular_function	pre-mRNA intronic binding
B	0000166	molecular_function	nucleotide binding
B	0000244	biological_process	spliceosomal tri-snRNP complex assembly
B	0000398	biological_process	mRNA splicing, via spliceosome
B	0000974	cellular_component	Prp19 complex
B	0003924	molecular_function	GTPase activity
B	0005515	molecular_function	protein binding
B	0005525	molecular_function	GTP binding
B	0005634	cellular_component	nucleus
B	0005681	cellular_component	spliceosomal complex
B	0005682	cellular_component	U5 snRNP
B	0005721	cellular_component	pericentric heterochromatin
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006397	biological_process	mRNA processing
B	0008380	biological_process	RNA splicing
B	0030623	molecular_function	U5 snRNA binding
B	0031047	biological_process	regulatory ncRNA-mediated gene silencing
B	0045292	biological_process	mRNA cis splicing, via spliceosome
B	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
B	0071007	cellular_component	U2-type catalytic step 2 spliceosome
B	0071014	cellular_component	post-mRNA release spliceosomal complex
B	0140727	biological_process	siRNA-mediated pericentric heterochromatin formation
C	0000375	biological_process	RNA splicing, via transesterification reactions
C	0003674	molecular_function	molecular_function
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005681	cellular_component	spliceosomal complex
C	0005682	cellular_component	U5 snRNP
C	0006397	biological_process	mRNA processing
C	0008380	biological_process	RNA splicing
C	0045292	biological_process	mRNA cis splicing, via spliceosome
C	0071013	cellular_component	catalytic step 2 spliceosome
C	0071014	cellular_component	post-mRNA release spliceosomal complex
D	0000243	cellular_component	commitment complex
D	0000387	biological_process	spliceosomal snRNP assembly
D	0000395	biological_process	mRNA 5'-splice site recognition
D	0003723	molecular_function	RNA binding
D	0003729	molecular_function	mRNA binding
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005681	cellular_component	spliceosomal complex
D	0005682	cellular_component	U5 snRNP
D	0005685	cellular_component	U1 snRNP
D	0005686	cellular_component	U2 snRNP
D	0005687	cellular_component	U4 snRNP
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006396	biological_process	RNA processing
D	0006397	biological_process	mRNA processing
D	0008380	biological_process	RNA splicing
D	0034719	cellular_component	SMN-Sm protein complex
D	0045292	biological_process	mRNA cis splicing, via spliceosome
D	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
D	0071004	cellular_component	U2-type prespliceosome
D	0071011	cellular_component	precatalytic spliceosome
D	0071013	cellular_component	catalytic step 2 spliceosome
D	0071014	cellular_component	post-mRNA release spliceosomal complex
D	0097526	cellular_component	spliceosomal tri-snRNP complex
D	1990904	cellular_component	ribonucleoprotein complex
E	0000395	biological_process	mRNA 5'-splice site recognition
E	0000398	biological_process	mRNA splicing, via spliceosome
E	0003723	molecular_function	RNA binding
E	0005634	cellular_component	nucleus
E	0005681	cellular_component	spliceosomal complex
E	0005682	cellular_component	U5 snRNP
E	0005685	cellular_component	U1 snRNP
E	0005686	cellular_component	U2 snRNP
E	0005687	cellular_component	U4 snRNP
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0006397	biological_process	mRNA processing
E	0008380	biological_process	RNA splicing
E	0032991	cellular_component	protein-containing complex
E	0045292	biological_process	mRNA cis splicing, via spliceosome
E	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
E	0070990	molecular_function	snRNP binding
E	0071004	cellular_component	U2-type prespliceosome
E	0071013	cellular_component	catalytic step 2 spliceosome
E	0071014	cellular_component	post-mRNA release spliceosomal complex
E	1990904	cellular_component	ribonucleoprotein complex
F	0000243	cellular_component	commitment complex
F	0000387	biological_process	spliceosomal snRNP assembly
F	0000395	biological_process	mRNA 5'-splice site recognition
F	0003723	molecular_function	RNA binding
F	0003729	molecular_function	mRNA binding
F	0005515	molecular_function	protein binding
F	0005634	cellular_component	nucleus
F	0005681	cellular_component	spliceosomal complex
F	0005682	cellular_component	U5 snRNP
F	0005685	cellular_component	U1 snRNP
F	0005686	cellular_component	U2 snRNP
F	0005687	cellular_component	U4 snRNP
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0006396	biological_process	RNA processing
F	0006397	biological_process	mRNA processing
F	0008380	biological_process	RNA splicing
F	0034715	cellular_component	pICln-Sm protein complex
F	0034719	cellular_component	SMN-Sm protein complex
F	0045292	biological_process	mRNA cis splicing, via spliceosome
F	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
F	0071004	cellular_component	U2-type prespliceosome
F	0071011	cellular_component	precatalytic spliceosome
F	0071013	cellular_component	catalytic step 2 spliceosome
F	0071014	cellular_component	post-mRNA release spliceosomal complex
F	0097525	cellular_component	spliceosomal snRNP complex
F	0097526	cellular_component	spliceosomal tri-snRNP complex
F	1990904	cellular_component	ribonucleoprotein complex
G	0000387	biological_process	spliceosomal snRNP assembly
G	0000395	biological_process	mRNA 5'-splice site recognition
G	0000398	biological_process	mRNA splicing, via spliceosome
G	0000974	cellular_component	Prp19 complex
G	0003723	molecular_function	RNA binding
G	0005634	cellular_component	nucleus
G	0005681	cellular_component	spliceosomal complex
G	0005682	cellular_component	U5 snRNP
G	0005685	cellular_component	U1 snRNP
G	0005686	cellular_component	U2 snRNP
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0006397	biological_process	mRNA processing
G	0008380	biological_process	RNA splicing
G	0030532	cellular_component	small nuclear ribonucleoprotein complex
G	0034715	cellular_component	pICln-Sm protein complex
G	0045292	biological_process	mRNA cis splicing, via spliceosome
G	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
G	0071004	cellular_component	U2-type prespliceosome
G	0071011	cellular_component	precatalytic spliceosome
G	0071013	cellular_component	catalytic step 2 spliceosome
G	0071014	cellular_component	post-mRNA release spliceosomal complex
G	1990904	cellular_component	ribonucleoprotein complex
H	0000387	biological_process	spliceosomal snRNP assembly
H	0000395	biological_process	mRNA 5'-splice site recognition
H	0000398	biological_process	mRNA splicing, via spliceosome
H	0003723	molecular_function	RNA binding
H	0005634	cellular_component	nucleus
H	0005681	cellular_component	spliceosomal complex
H	0005682	cellular_component	U5 snRNP
H	0005685	cellular_component	U1 snRNP
H	0005686	cellular_component	U2 snRNP
H	0005687	cellular_component	U4 snRNP
H	0005737	cellular_component	cytoplasm
H	0005829	cellular_component	cytosol
H	0006397	biological_process	mRNA processing
H	0008380	biological_process	RNA splicing
H	0032991	cellular_component	protein-containing complex
H	0034715	cellular_component	pICln-Sm protein complex
H	0045292	biological_process	mRNA cis splicing, via spliceosome
H	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
H	0071004	cellular_component	U2-type prespliceosome
H	0071011	cellular_component	precatalytic spliceosome
H	0071014	cellular_component	post-mRNA release spliceosomal complex
H	1990904	cellular_component	ribonucleoprotein complex
I	0000395	biological_process	mRNA 5'-splice site recognition
I	0000398	biological_process	mRNA splicing, via spliceosome
I	0003723	molecular_function	RNA binding
I	0005634	cellular_component	nucleus
I	0005681	cellular_component	spliceosomal complex
I	0005682	cellular_component	U5 snRNP
I	0005685	cellular_component	U1 snRNP
I	0005686	cellular_component	U2 snRNP
I	0005737	cellular_component	cytoplasm
I	0005829	cellular_component	cytosol
I	0006397	biological_process	mRNA processing
I	0008380	biological_process	RNA splicing
I	0022618	biological_process	protein-RNA complex assembly
I	0034715	cellular_component	pICln-Sm protein complex
I	0045292	biological_process	mRNA cis splicing, via spliceosome
I	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
I	0071013	cellular_component	catalytic step 2 spliceosome
I	0071014	cellular_component	post-mRNA release spliceosomal complex
I	1990904	cellular_component	ribonucleoprotein complex
J	0000395	biological_process	mRNA 5'-splice site recognition
J	0000398	biological_process	mRNA splicing, via spliceosome
J	0003723	molecular_function	RNA binding
J	0005634	cellular_component	nucleus
J	0005681	cellular_component	spliceosomal complex
J	0005682	cellular_component	U5 snRNP
J	0005685	cellular_component	U1 snRNP
J	0005686	cellular_component	U2 snRNP
J	0005687	cellular_component	U4 snRNP
J	0005737	cellular_component	cytoplasm
J	0005829	cellular_component	cytosol
J	0006397	biological_process	mRNA processing
J	0008380	biological_process	RNA splicing
J	0032991	cellular_component	protein-containing complex
J	0034719	cellular_component	SMN-Sm protein complex
J	0045292	biological_process	mRNA cis splicing, via spliceosome
J	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
J	0071004	cellular_component	U2-type prespliceosome
J	0071011	cellular_component	precatalytic spliceosome
J	0071013	cellular_component	catalytic step 2 spliceosome
J	0071014	cellular_component	post-mRNA release spliceosomal complex
J	0097526	cellular_component	spliceosomal tri-snRNP complex
J	1990904	cellular_component	ribonucleoprotein complex
K	0000398	biological_process	mRNA splicing, via spliceosome
K	0000974	cellular_component	Prp19 complex
K	0003674	molecular_function	molecular_function
K	0005515	molecular_function	protein binding
K	0005634	cellular_component	nucleus
K	0005681	cellular_component	spliceosomal complex
K	0006397	biological_process	mRNA processing
K	0008380	biological_process	RNA splicing
K	0045292	biological_process	mRNA cis splicing, via spliceosome
K	0071013	cellular_component	catalytic step 2 spliceosome
K	0071014	cellular_component	post-mRNA release spliceosomal complex
L	0000398	biological_process	mRNA splicing, via spliceosome
L	0000974	cellular_component	Prp19 complex
L	0003723	molecular_function	RNA binding
L	0005515	molecular_function	protein binding
L	0005634	cellular_component	nucleus
L	0005681	cellular_component	spliceosomal complex
L	0006397	biological_process	mRNA processing
L	0008380	biological_process	RNA splicing
L	0045292	biological_process	mRNA cis splicing, via spliceosome
L	0060090	molecular_function	molecular adaptor activity
L	0071014	cellular_component	post-mRNA release spliceosomal complex
M	0000974	cellular_component	Prp19 complex
M	0003676	molecular_function	nucleic acid binding
M	0003723	molecular_function	RNA binding
M	0005515	molecular_function	protein binding
M	0005634	cellular_component	nucleus
M	0005681	cellular_component	spliceosomal complex
M	0006397	biological_process	mRNA processing
M	0008380	biological_process	RNA splicing
M	0017070	molecular_function	U6 snRNA binding
M	0036002	molecular_function	pre-mRNA binding
M	0045292	biological_process	mRNA cis splicing, via spliceosome
M	0071006	cellular_component	U2-type catalytic step 1 spliceosome
M	0071007	cellular_component	U2-type catalytic step 2 spliceosome
M	0071014	cellular_component	post-mRNA release spliceosomal complex
N	0000398	biological_process	mRNA splicing, via spliceosome
N	0000974	cellular_component	Prp19 complex
N	0003729	molecular_function	mRNA binding
N	0005515	molecular_function	protein binding
N	0005634	cellular_component	nucleus
N	0005681	cellular_component	spliceosomal complex
N	0005684	cellular_component	U2-type spliceosomal complex
N	0006397	biological_process	mRNA processing
N	0008380	biological_process	RNA splicing
N	0045292	biological_process	mRNA cis splicing, via spliceosome
N	0071013	cellular_component	catalytic step 2 spliceosome
N	0071014	cellular_component	post-mRNA release spliceosomal complex
O	0000398	biological_process	mRNA splicing, via spliceosome
O	0000974	cellular_component	Prp19 complex
O	0003674	molecular_function	molecular_function
O	0005634	cellular_component	nucleus
O	0005681	cellular_component	spliceosomal complex
O	0005684	cellular_component	U2-type spliceosomal complex
O	0006397	biological_process	mRNA processing
O	0008380	biological_process	RNA splicing
O	0045292	biological_process	mRNA cis splicing, via spliceosome
O	0071014	cellular_component	post-mRNA release spliceosomal complex
P	0000387	biological_process	spliceosomal snRNP assembly
P	0000974	cellular_component	Prp19 complex
P	0003676	molecular_function	nucleic acid binding
P	0003723	molecular_function	RNA binding
P	0005515	molecular_function	protein binding
P	0005634	cellular_component	nucleus
P	0005681	cellular_component	spliceosomal complex
P	0006397	biological_process	mRNA processing
P	0008270	molecular_function	zinc ion binding
P	0008380	biological_process	RNA splicing
P	0016071	biological_process	mRNA metabolic process
P	0017070	molecular_function	U6 snRNA binding
P	0036002	molecular_function	pre-mRNA binding
P	0045292	biological_process	mRNA cis splicing, via spliceosome
P	0046872	molecular_function	metal ion binding
P	0071006	cellular_component	U2-type catalytic step 1 spliceosome
P	0071007	cellular_component	U2-type catalytic step 2 spliceosome
P	0071014	cellular_component	post-mRNA release spliceosomal complex
Q	0000398	biological_process	mRNA splicing, via spliceosome
Q	0000974	cellular_component	Prp19 complex
Q	0003723	molecular_function	RNA binding
Q	0005634	cellular_component	nucleus
Q	0005681	cellular_component	spliceosomal complex
Q	0006397	biological_process	mRNA processing
Q	0008380	biological_process	RNA splicing
Q	0045292	biological_process	mRNA cis splicing, via spliceosome
Q	0071013	cellular_component	catalytic step 2 spliceosome
Q	0071014	cellular_component	post-mRNA release spliceosomal complex
R	0000245	biological_process	spliceosomal complex assembly
R	0000398	biological_process	mRNA splicing, via spliceosome
R	0000974	cellular_component	Prp19 complex
R	0003674	molecular_function	molecular_function
R	0005515	molecular_function	protein binding
R	0005634	cellular_component	nucleus
R	0005681	cellular_component	spliceosomal complex
R	0006396	biological_process	RNA processing
R	0006397	biological_process	mRNA processing
R	0008380	biological_process	RNA splicing
R	0045292	biological_process	mRNA cis splicing, via spliceosome
R	0071004	cellular_component	U2-type prespliceosome
R	0071007	cellular_component	U2-type catalytic step 2 spliceosome
R	0071014	cellular_component	post-mRNA release spliceosomal complex
S	0000398	biological_process	mRNA splicing, via spliceosome
S	0000974	cellular_component	Prp19 complex
S	0004842	molecular_function	ubiquitin-protein transferase activity
S	0005515	molecular_function	protein binding
S	0005634	cellular_component	nucleus
S	0005635	cellular_component	nuclear envelope
S	0005681	cellular_component	spliceosomal complex
S	0005737	cellular_component	cytoplasm
S	0005829	cellular_component	cytosol
S	0006281	biological_process	DNA repair
S	0006397	biological_process	mRNA processing
S	0006974	biological_process	DNA damage response
S	0008380	biological_process	RNA splicing
S	0016567	biological_process	protein ubiquitination
S	0016740	molecular_function	transferase activity
S	0045292	biological_process	mRNA cis splicing, via spliceosome
S	0061630	molecular_function	ubiquitin protein ligase activity
S	0070534	biological_process	protein K63-linked ubiquitination
S	0071006	cellular_component	U2-type catalytic step 1 spliceosome
S	0071014	cellular_component	post-mRNA release spliceosomal complex
T	0000398	biological_process	mRNA splicing, via spliceosome
T	0000974	cellular_component	Prp19 complex
T	0004842	molecular_function	ubiquitin-protein transferase activity
T	0005515	molecular_function	protein binding
T	0005634	cellular_component	nucleus
T	0005635	cellular_component	nuclear envelope
T	0005681	cellular_component	spliceosomal complex
T	0005737	cellular_component	cytoplasm
T	0005829	cellular_component	cytosol
T	0006281	biological_process	DNA repair
T	0006397	biological_process	mRNA processing
T	0006974	biological_process	DNA damage response
T	0008380	biological_process	RNA splicing
T	0016567	biological_process	protein ubiquitination
T	0016740	molecular_function	transferase activity
T	0045292	biological_process	mRNA cis splicing, via spliceosome
T	0061630	molecular_function	ubiquitin protein ligase activity
T	0070534	biological_process	protein K63-linked ubiquitination
T	0071006	cellular_component	U2-type catalytic step 1 spliceosome
T	0071014	cellular_component	post-mRNA release spliceosomal complex
U	0000398	biological_process	mRNA splicing, via spliceosome
U	0000974	cellular_component	Prp19 complex
U	0004842	molecular_function	ubiquitin-protein transferase activity
U	0005515	molecular_function	protein binding
U	0005634	cellular_component	nucleus
U	0005635	cellular_component	nuclear envelope
U	0005681	cellular_component	spliceosomal complex
U	0005737	cellular_component	cytoplasm
U	0005829	cellular_component	cytosol
U	0006281	biological_process	DNA repair
U	0006397	biological_process	mRNA processing
U	0006974	biological_process	DNA damage response
U	0008380	biological_process	RNA splicing
U	0016567	biological_process	protein ubiquitination
U	0016740	molecular_function	transferase activity
U	0045292	biological_process	mRNA cis splicing, via spliceosome
U	0061630	molecular_function	ubiquitin protein ligase activity
U	0070534	biological_process	protein K63-linked ubiquitination
U	0071006	cellular_component	U2-type catalytic step 1 spliceosome
U	0071014	cellular_component	post-mRNA release spliceosomal complex
V	0000398	biological_process	mRNA splicing, via spliceosome
V	0000974	cellular_component	Prp19 complex
V	0004842	molecular_function	ubiquitin-protein transferase activity
V	0005515	molecular_function	protein binding
V	0005634	cellular_component	nucleus
V	0005635	cellular_component	nuclear envelope
V	0005681	cellular_component	spliceosomal complex
V	0005737	cellular_component	cytoplasm
V	0005829	cellular_component	cytosol
V	0006281	biological_process	DNA repair
V	0006397	biological_process	mRNA processing
V	0006974	biological_process	DNA damage response
V	0008380	biological_process	RNA splicing
V	0016567	biological_process	protein ubiquitination
V	0016740	molecular_function	transferase activity
V	0045292	biological_process	mRNA cis splicing, via spliceosome
V	0061630	molecular_function	ubiquitin protein ligase activity
V	0070534	biological_process	protein K63-linked ubiquitination
V	0071006	cellular_component	U2-type catalytic step 1 spliceosome
V	0071014	cellular_component	post-mRNA release spliceosomal complex
W	0000398	biological_process	mRNA splicing, via spliceosome
W	0000974	cellular_component	Prp19 complex
W	0003677	molecular_function	DNA binding
W	0005515	molecular_function	protein binding
W	0005634	cellular_component	nucleus
W	0005681	cellular_component	spliceosomal complex
W	0005829	cellular_component	cytosol
W	0006397	biological_process	mRNA processing
W	0008380	biological_process	RNA splicing
W	0045292	biological_process	mRNA cis splicing, via spliceosome
W	0071014	cellular_component	post-mRNA release spliceosomal complex
W	0140602	cellular_component	nucleolar peripheral inclusion body
X	0000349	biological_process	generation of catalytic spliceosome for first transesterification step
X	0000398	biological_process	mRNA splicing, via spliceosome
X	0000974	cellular_component	Prp19 complex
X	0003674	molecular_function	molecular_function
X	0005515	molecular_function	protein binding
X	0005634	cellular_component	nucleus
X	0005681	cellular_component	spliceosomal complex
X	0005829	cellular_component	cytosol
X	0006396	biological_process	RNA processing
X	0006397	biological_process	mRNA processing
X	0008380	biological_process	RNA splicing
X	0045292	biological_process	mRNA cis splicing, via spliceosome
X	0071004	cellular_component	U2-type prespliceosome
X	0071007	cellular_component	U2-type catalytic step 2 spliceosome
X	0071014	cellular_component	post-mRNA release spliceosomal complex
Y	0000974	cellular_component	Prp19 complex
Y	0003674	molecular_function	molecular_function
Y	0005634	cellular_component	nucleus
Y	0005681	cellular_component	spliceosomal complex
Y	0006397	biological_process	mRNA processing
Y	0008380	biological_process	RNA splicing
Y	0045292	biological_process	mRNA cis splicing, via spliceosome
Y	0071004	cellular_component	U2-type prespliceosome
Y	0071013	cellular_component	catalytic step 2 spliceosome
Y	0071014	cellular_component	post-mRNA release spliceosomal complex
Z	0000974	cellular_component	Prp19 complex
Z	0003674	molecular_function	molecular_function
Z	0005515	molecular_function	protein binding
Z	0005634	cellular_component	nucleus
Z	0005681	cellular_component	spliceosomal complex
Z	0006397	biological_process	mRNA processing
Z	0008380	biological_process	RNA splicing
Z	0045292	biological_process	mRNA cis splicing, via spliceosome
Z	0071013	cellular_component	catalytic step 2 spliceosome
Z	0071014	cellular_component	post-mRNA release spliceosomal complex
a	0000398	biological_process	mRNA splicing, via spliceosome
a	0000974	cellular_component	Prp19 complex
a	0003729	molecular_function	mRNA binding
a	0005515	molecular_function	protein binding
a	0005634	cellular_component	nucleus
a	0005681	cellular_component	spliceosomal complex
a	0006397	biological_process	mRNA processing
a	0008380	biological_process	RNA splicing
a	0045292	biological_process	mRNA cis splicing, via spliceosome
a	0071013	cellular_component	catalytic step 2 spliceosome
a	0071014	cellular_component	post-mRNA release spliceosomal complex
b	0000974	cellular_component	Prp19 complex
b	0003674	molecular_function	molecular_function
b	0005634	cellular_component	nucleus
b	0005681	cellular_component	spliceosomal complex
b	0005684	cellular_component	U2-type spliceosomal complex
b	0005737	cellular_component	cytoplasm
b	0006397	biological_process	mRNA processing
b	0008380	biological_process	RNA splicing
b	0045292	biological_process	mRNA cis splicing, via spliceosome
c	0000398	biological_process	mRNA splicing, via spliceosome
c	0000974	cellular_component	Prp19 complex
c	0003723	molecular_function	RNA binding
c	0005634	cellular_component	nucleus
c	0005681	cellular_component	spliceosomal complex
c	0005684	cellular_component	U2-type spliceosomal complex
c	0005737	cellular_component	cytoplasm
c	0006397	biological_process	mRNA processing
c	0008380	biological_process	RNA splicing
c	0045292	biological_process	mRNA cis splicing, via spliceosome
c	0071013	cellular_component	catalytic step 2 spliceosome
d	0000398	biological_process	mRNA splicing, via spliceosome
d	0000413	biological_process	protein peptidyl-prolyl isomerization
d	0000974	cellular_component	Prp19 complex
d	0003755	molecular_function	peptidyl-prolyl cis-trans isomerase activity
d	0005515	molecular_function	protein binding
d	0005634	cellular_component	nucleus
d	0005681	cellular_component	spliceosomal complex
d	0005829	cellular_component	cytosol
d	0006457	biological_process	protein folding
d	0016853	molecular_function	isomerase activity
d	0045292	biological_process	mRNA cis splicing, via spliceosome
d	0071013	cellular_component	catalytic step 2 spliceosome
d	0071014	cellular_component	post-mRNA release spliceosomal complex
e	0005515	molecular_function	protein binding
e	0005634	cellular_component	nucleus
e	0005737	cellular_component	cytoplasm
e	0005819	cellular_component	spindle
e	0005856	cellular_component	cytoskeleton
e	0005874	cellular_component	microtubule
e	0045292	biological_process	mRNA cis splicing, via spliceosome
e	0071013	cellular_component	catalytic step 2 spliceosome
e	0071014	cellular_component	post-mRNA release spliceosomal complex
m	0000390	biological_process	spliceosomal complex disassembly
m	0003676	molecular_function	nucleic acid binding
m	0003723	molecular_function	RNA binding
m	0005515	molecular_function	protein binding
m	0005634	cellular_component	nucleus
m	0005681	cellular_component	spliceosomal complex
m	0005737	cellular_component	cytoplasm
m	0005816	cellular_component	spindle pole body
m	0005856	cellular_component	cytoskeleton
m	0045292	biological_process	mRNA cis splicing, via spliceosome
m	0071008	cellular_component	U2-type post-mRNA release spliceosomal complex
m	0071014	cellular_component	post-mRNA release spliceosomal complex
n	0000390	biological_process	spliceosomal complex disassembly
n	0003674	molecular_function	molecular_function
n	0005634	cellular_component	nucleus
n	0005737	cellular_component	cytoplasm
n	0005829	cellular_component	cytosol
n	0071008	cellular_component	U2-type post-mRNA release spliceosomal complex
p	0000398	biological_process	mRNA splicing, via spliceosome
p	0003674	molecular_function	molecular_function
p	0005634	cellular_component	nucleus
p	0005681	cellular_component	spliceosomal complex
p	0005684	cellular_component	U2-type spliceosomal complex
p	0006397	biological_process	mRNA processing
p	0008380	biological_process	RNA splicing
p	0045292	biological_process	mRNA cis splicing, via spliceosome
p	0071014	cellular_component	post-mRNA release spliceosomal complex
y	0003723	molecular_function	RNA binding
y	0005634	cellular_component	nucleus
y	0005681	cellular_component	spliceosomal complex
y	0005737	cellular_component	cytoplasm
y	0005829	cellular_component	cytosol
y	0006397	biological_process	mRNA processing
y	0030674	molecular_function	protein-macromolecule adaptor activity
y	0045292	biological_process	mRNA cis splicing, via spliceosome
z	0000166	molecular_function	nucleotide binding
z	0000398	biological_process	mRNA splicing, via spliceosome
z	0003676	molecular_function	nucleic acid binding
z	0003723	molecular_function	RNA binding
z	0003724	molecular_function	RNA helicase activity
z	0004386	molecular_function	helicase activity
z	0005524	molecular_function	ATP binding
z	0005634	cellular_component	nucleus
z	0005681	cellular_component	spliceosomal complex
z	0005829	cellular_component	cytosol
z	0006397	biological_process	mRNA processing
z	0008380	biological_process	RNA splicing
z	0016787	molecular_function	hydrolase activity
z	0016887	molecular_function	ATP hydrolysis activity
z	0045292	biological_process	mRNA cis splicing, via spliceosome
z	0071013	cellular_component	catalytic step 2 spliceosome

Functional Information from PROSITE/UniProt

site_id	PS00170
Number of Residues	18
Details	CSA_PPIASE_1 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. YdgViFHRVIpdFViQGG

Chain	Residue	Details
d	TYR38-GLY55

---

site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. LLSGsmDnQIKIWEV

Chain	Residue	Details
a	LEU282-VAL296
K	LEU262-MET276
K	VAL304-LEU318
S	VAL391-LEU405
C	LEU151-SER165
C	VAL192-LEU206

---

site_id	PS00690
Number of Residues	10
Details	DEAH_ATP_HELICASE DEAH-box subfamily ATP-dependent helicases signature. SiVILDEVHE

Chain	Residue	Details
z	SER141-GLU150

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	15
Details	Compositional bias: {"description":"Basic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"18257517","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	263
Details	Domain: {"description":"tr-type G","evidences":[{"source":"PROSITE-ProRule","id":"PRU01059","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	7
Details	Region: {"description":"G1","evidences":[{"source":"PROSITE-ProRule","id":"PRU01059","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	4
Details	Region: {"description":"G2","evidences":[{"source":"PROSITE-ProRule","id":"PRU01059","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	3
Details	Region: {"description":"G3","evidences":[{"source":"PROSITE-ProRule","id":"PRU01059","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	3
Details	Region: {"description":"G4","evidences":[{"source":"PROSITE-ProRule","id":"PRU01059","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	2
Details	Region: {"description":"G5","evidences":[{"source":"PROSITE-ProRule","id":"PRU01059","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	14
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	108
Details	Repeat: {"description":"WD 1"}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	69
Details	Repeat: {"description":"WD 2"}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	69
Details	Repeat: {"description":"WD 4"}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	68
Details	Repeat: {"description":"WD 5"}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	68
Details	Repeat: {"description":"WD 6"}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	215
Details	Domain: {"description":"Sm","evidences":[{"source":"PROSITE-ProRule","id":"PRU01346","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI16
Number of Residues	30
Details	Repeat: {"description":"WD 3"}

Chain

Residue

Details

---

site_id	SWS_FT_FI17
Number of Residues	30
Details	Repeat: {"description":"WD 7"}

Chain

Residue

Details

---

site_id	SWS_FT_FI18
Number of Residues	71
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI19
Number of Residues	11
Details	Compositional bias: {"description":"Pro residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI20
Number of Residues	51
Details	Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI21
Number of Residues	3
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18257517","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI22
Number of Residues	27
Details	Zinc finger: {"description":"C3H1-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00723","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI23
Number of Residues	32
Details	Repeat: {"description":"HAT 1"}

Chain

Residue

Details

---

site_id	SWS_FT_FI24
Number of Residues	32
Details	Repeat: {"description":"HAT 2"}

Chain

Residue

Details

---

site_id	SWS_FT_FI25
Number of Residues	64
Details	Repeat: {"description":"HAT 3"}

Chain

Residue

Details

---

site_id	SWS_FT_FI26
Number of Residues	65
Details	Repeat: {"description":"HAT 4"}

Chain

Residue

Details

---

site_id	SWS_FT_FI27
Number of Residues	62
Details	Repeat: {"description":"HAT 5"}

Chain

Residue

Details

---

site_id	SWS_FT_FI28
Number of Residues	35
Details	Repeat: {"description":"HAT 6"}

Chain

Residue

Details

---

site_id	SWS_FT_FI29
Number of Residues	67
Details	Repeat: {"description":"HAT 7"}

Chain

Residue

Details

---

site_id	SWS_FT_FI30
Number of Residues	67
Details	Repeat: {"description":"HAT 8"}

Chain

Residue

Details

---

site_id	SWS_FT_FI31
Number of Residues	34
Details	Repeat: {"description":"HAT 9"}

Chain

Residue

Details

---

site_id	SWS_FT_FI32
Number of Residues	31
Details	Repeat: {"description":"HAT 11"}

Chain

Residue

Details

---

site_id	SWS_FT_FI33
Number of Residues	67
Details	Repeat: {"description":"HAT 12"}

Chain

Residue

Details

---

site_id	SWS_FT_FI34
Number of Residues	66
Details	Repeat: {"description":"HAT 13"}

Chain

Residue

Details

---

site_id	SWS_FT_FI35
Number of Residues	65
Details	Repeat: {"description":"HAT 14"}

Chain

Residue

Details

---

site_id	SWS_FT_FI36
Number of Residues	75
Details	Repeat: {"description":"HAT 15"}

Chain

Residue

Details

---

site_id	SWS_FT_FI37
Number of Residues	280
Details	Domain: {"description":"U-box"}

Chain

Residue

Details

---

site_id	SWS_FT_FI38
Number of Residues	49
Details	Domain: {"description":"HTH myb-type 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00625","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI39
Number of Residues	45
Details	DNA binding: {"description":"H-T-H motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU00625","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI40
Number of Residues	34
Details	Repeat: {"description":"HAT 10"}

Chain

Residue

Details

---

site_id	SWS_FT_FI41
Number of Residues	116
Details	Domain: {"description":"MI","evidences":[{"source":"PROSITE-ProRule","id":"PRU00698","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI42
Number of Residues	164
Details	Domain: {"description":"Helicase ATP-binding","evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI43
Number of Residues	179
Details	Domain: {"description":"Helicase C-terminal","evidences":[{"source":"PROSITE-ProRule","id":"PRU00542","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI44
Number of Residues	3
Details	Motif: {"description":"DEAH box"}

Chain

Residue

Details

---

site_id	SWS_FT_FI45
Number of Residues	7
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---