9EQM
Crystal structure of pVHL:EloB:EloC in complex with MP-1-21
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Elongin-B | polymer | 104 | 11748.4 | 1 | UniProt (Q15370) In PDB | Homo sapiens (human) | EloB,Elongin 18 kDa subunit,RNA polymerase II transcription factor SIII subunit B,SIII p18,Transcription elongation factor B polypeptide 2 |
| 2 | B | Elongin-C | polymer | 97 | 10974.6 | 1 | UniProt (Q15369) In PDB | Homo sapiens (human) | EloC,Elongin 15 kDa subunit,RNA polymerase II transcription factor SIII subunit C,SIII p15,Transcription elongation factor B polypeptide 1 |
| 3 | C | von Hippel-Lindau disease tumor suppressor | polymer | 162 | 18702.3 | 1 | UniProt (P40337) In PDB | Homo sapiens (human) | Protein G7,pVHL |
| 4 | C | (2S,4R)-1-[(2R)-2-[(1-fluoranylcyclopropyl)carbonylamino]-3-methyl-3-[[trans-4-(morpholin-4-ylmethyl)cyclohexyl]methylsulfanyl]butanoyl]-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]-4-oxidanyl-pyrrolidine-2-carboxamide | non-polymer | 730.0 | 1 | Chemie (A1H9F) | |||
| 5 | water | water | 18.0 | 41 | Chemie (HOH) |
Sequence modifications
B: 17 - 112 (UniProt: Q15369)
C: 54 - 213 (UniProt: P40337)
| PDB | External Database | Details |
|---|---|---|
| Met 16 | - | initiating methionine |
| PDB | External Database | Details |
|---|---|---|
| Gly 52 | - | expression tag |
| Ser 53 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 41425.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 730.0 | |
| All* | Total formula weight | 42155.3 |
