9EOY
Structure of Thr354Asn, Glu355Gln, Thr412Asn, Ile414Met, Ile464His, and Phe467Met mutant human CaMKII alpha hub bound to PIPA
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... | Calcium/calmodulin-dependent protein kinase type II subunit alpha | polymer | 135 | 15551.6 | 7 | UniProt (Q9UQM7) In PDB | Homo sapiens (human) | CaM kinase II subunit alpha,CaMK-II subunit alpha |
| 2 | A, B, C, E, F... | ACETATE ION | non-polymer | 59.0 | 6 | Chemie (ACT) | |||
| 3 | C, D | 2-[6-(4-chlorophenyl)imidazo[1,2-b]pyridazin-2-yl]ethanoic acid | non-polymer | 287.7 | 2 | Chemie (A1H6K) | |||
| 4 | C | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
| 5 | water | water | 18.0 | 102 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G: 345 - 475 (UniProt: Q9UQM7)
| PDB | External Database | Details |
|---|---|---|
| Gly 341 | - | expression tag |
| Pro 342 | - | expression tag |
| His 343 | - | expression tag |
| Met 344 | - | expression tag |
| Asn 354 | Thr 354 | engineered mutation |
| Gln 355 | Glu 355 | engineered mutation |
| Asn 412 | Thr 412 | engineered mutation |
| Met 414 | Ile 414 | engineered mutation |
| His 464 | Ile 464 | engineered mutation |
| Met 467 | Phe 467 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 7 |
| Total formula weight | 108861.0 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1123.9 | |
| All* | Total formula weight | 109984.9 |
