9EOT
Structure of human ceramide synthase 6 (CerS6) bound to C16:0 (nanobody Nb02)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, C) | Isoform 2 of Ceramide synthase 6 | polymer | 357 | 42418.3 | 2 | UniProt (Q6ZMG9) Pfam (PF00046) Pfam (PF03798) | Homo sapiens (human) | CerS6,LAG1 longevity assurance homolog 6,Sphingoid base N-palmitoyltransferase CERS6 |
| 2 | B, C (B, D) | Nanobody-02 | polymer | 134 | 14834.4 | 2 | Vicugna pacos | ||
| 3 | E, H (A, C) | PALMITIC ACID | non-polymer | 256.4 | 2 | Chemie (PLM) | |||
| 4 | F, I (A, C) | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE | non-polymer | 790.1 | 2 | Chemie (PC1) | |||
| 5 | G, J (A, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) |
Sequence modifications
A, C: 1 - 350 (UniProt: Q6ZMG9)
| PDB | External Database | Details |
|---|---|---|
| Ala 351 | - | expression tag |
| Glu 352 | - | expression tag |
| Asn 353 | - | expression tag |
| Leu 354 | - | expression tag |
| Tyr 355 | - | expression tag |
| Phe 356 | - | expression tag |
| Gln 357 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 114505.4 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 2535.6 | |
| All* | Total formula weight | 117041.0 |
