9EMD
Crystal structure of Histidine acetyltransferase with L-histidine and coenzyme A disulfide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Probable N-acetyltransferase 16 | polymer | 352 | 39038.5 | 1 | UniProt (Q8N8M0) Pfam (PF00583) | Homo sapiens (human) | |
| 2 | B, E, G, H (A) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 3 | C (A) | [[(2~{S},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(3~{R})-4-[[3-[2-[2-[3-[[(2~{R})-4-[[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,3-dimethyl-2-oxidanyl-butanoyl]amino]propanoylamino]ethyldisulfanyl]ethylamino]-3-oxidanylidene-propyl]amino]-2,2-dimethyl-3-oxidanyl-4-oxidanylidene-butyl] hydrogen phosphate | non-polymer | 1533.1 | 1 | Chemie (5NG) | |||
| 4 | D (A) | MALONATE ION | non-polymer | 102.0 | 1 | Chemie (MLI) | |||
| 5 | F (A) | HISTIDINE | non-polymer | 156.2 | 1 | Chemie (HIS) | |||
| 6 | I (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 7 | J (A) | water | water | 18.0 | 342 | Chemie (HOH) |
Sequence modifications
A: 24 - 369 (UniProt: Q8N8M0)
| PDB | External Database | Details |
|---|---|---|
| - | Ala 5 | deletion |
| - | Ser 6 | deletion |
| - | Cys 7 | deletion |
| - | Gly 8 | deletion |
| - | Thr 9 | deletion |
| - | Ala 10 | deletion |
| - | Thr 11 | deletion |
| - | Ser 12 | deletion |
| - | Glu 13 | deletion |
| - | Val 14 | deletion |
| - | Pro 15 | deletion |
| - | Lys 16 | deletion |
| - | Pro 17 | deletion |
| - | Glu 18 | deletion |
| - | Lys 19 | deletion |
| - | Lys 20 | deletion |
| - | Thr 21 | deletion |
| - | Ala 22 | deletion |
| - | Arg 23 | deletion |
| - | Asp 24 | deletion |
| - | Ala 25 | deletion |
| - | Glu 26 | deletion |
| - | Pro 27 | deletion |
| His 370 | - | expression tag |
| His 371 | - | expression tag |
| His 372 | - | expression tag |
| His 373 | - | expression tag |
| His 374 | - | expression tag |
| His 375 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 39038.5 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 2195.1 | |
| All* | Total formula weight | 41233.6 |
