9EKD

Structure of a C1r Zymogen Fragment Bound to SALO

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, B)	Salivary anti-complement protein	polymer	104	12205.4	2	UniProt (Q5WPZ4)	Lutzomyia longipalpis	10.7 kDa salivary protein,LJM19,Salivary anti-complement from Lu.longipalpis,SALO
2	B, D (C, D)	Complement C1r subcomponent	polymer	409	46617.5	2	UniProt (P00736) Pfam (PF00084) Pfam (PF00089)	Homo sapiens (human)	Complement component 1 subcomponent r

Sequence modifications

A, B: 23 - 115 (UniProt: Q5WPZ4)

PDB	External Database	Details
Gly 116	-	expression tag
Ser 117	-	expression tag
Gly 118	-	expression tag
His 119	-	expression tag
His 120	-	expression tag
His 121	-	expression tag
His 122	-	expression tag
His 123	-	expression tag
His 124	-	expression tag
His 125	-	expression tag
His 126	-	expression tag

C, D: 308 - 705 (UniProt: P00736)

PDB	External Database	Details
Ala 654	Ser 654	engineered mutation
Gly 706	-	expression tag
Ser 707	-	expression tag
Gly 708	-	expression tag
His 709	-	expression tag
His 710	-	expression tag
His 711	-	expression tag
His 712	-	expression tag
His 713	-	expression tag
His 714	-	expression tag
His 715	-	expression tag
His 716	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	117645.9
All*	Total formula weight	117645.9

*Water molecules are not included.