9EKB
Cryo-EM structure of apo-form human DNA polymerase delta
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA polymerase delta catalytic subunit | polymer | 1107 | 123785.9 | 1 | UniProt (P28340) Pfam (PF24055) Pfam (PF03104) Pfam (PF00136) Pfam (PF14260) | Homo sapiens (human) | 3'-5' exodeoxyribonuclease,DNA polymerase subunit delta p125 |
| 2 | B (B) | DNA polymerase delta subunit 2 | polymer | 469 | 51338.2 | 1 | UniProt (P49005) Pfam (PF18018) Pfam (PF04042) | Homo sapiens (human) | DNA polymerase delta subunit p50 |
| 3 | C (C) | DNA polymerase delta subunit 3 | polymer | 466 | 51486.4 | 1 | UniProt (Q15054) Pfam (PF09507) | Homo sapiens (human) | DNA polymerase delta subunit C,DNA polymerase delta subunit p66,DNA polymerase delta subunit p68 |
| 4 | D (D) | DNA polymerase delta subunit 4 | polymer | 114 | 13409.2 | 1 | UniProt (Q9HCU8) Pfam (PF04081) | Homo sapiens (human) | DNA polymerase delta subunit p12 |
| 5 | E (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 6 | F (A) | IRON/SULFUR CLUSTER | non-polymer | 351.6 | 1 | Chemie (SF4) |
Sequence modifications
D: 1 - 107 (UniProt: Q9HCU8)
| PDB | External Database | Details |
|---|---|---|
| Glu 108 | - | expression tag |
| His 109 | - | expression tag |
| His 110 | - | expression tag |
| His 111 | - | expression tag |
| His 112 | - | expression tag |
| His 113 | - | expression tag |
| His 114 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 240019.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 417.0 | |
| All* | Total formula weight | 240436.7 |
