9EK7
Crystal structure of MAIT TCR in complex with MR1-5FdU
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Major histocompatibility complex class I-related gene protein | polymer | 271 | 31711.7 | 2 | UniProt (Q95460) Pfam (PF00129) Pfam (PF07654) | Homo sapiens (human) | MHC class I-related gene protein,Class I histocompatibility antigen-like protein |
| 2 | B, D (B, D) | TCR alpha | polymer | 204 | 22781.3 | 2 | Homo sapiens (human) | ||
| 3 | E, G (E, G) | TCR beta | polymer | 246 | 27677.8 | 2 | Homo sapiens (human) | ||
| 4 | F, H (F, H) | Beta-2-microglobulin | polymer | 100 | 11879.4 | 2 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (human) | |
| 5 | I (A) | 1-(2-deoxy-alpha-D-erythro-pentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione | non-polymer | 256.2 | 1 | Chemie (YC6) | |||
| 6 | J, M, P, R, T... (A, B, C, F) | GLYCEROL | non-polymer | 92.1 | 7 | Chemie (GOL) | |||
| 7 | K, L, O, S, U (A, B, C, E) | ACETATE ION | non-polymer | 59.0 | 5 | Chemie (ACT) | |||
| 8 | N (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 9 | Q (C) | THYMIDINE | non-polymer | 242.2 | 1 | Chemie (THM) | |||
| 10 | V, Y (E, G) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 11 | AA, BA, CA, DA, EA... (B, C, D, E, F...) | water | water | 18.0 | 966 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 270 (UniProt: Q95460)
F, H: 1 - 99 (UniProt: P61769)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
| Ser 261 | Cys 283 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 188100.1 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 1519.8 | |
| All* | Total formula weight | 189619.9 |
