9EK7
Crystal structure of MAIT TCR in complex with MR1-5FdU
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Major histocompatibility complex class I-related gene protein | polymer | 271 | 31711.7 | 2 | UniProt (Q95460) Pfam (PF00129) Pfam (PF07654) | Homo sapiens (human) | MHC class I-related gene protein,Class I histocompatibility antigen-like protein |
| 2 | B, D (B, D) | TCR alpha | polymer | 204 | 22781.3 | 2 | Homo sapiens (human) | ||
| 3 | E, G (E, G) | TCR beta | polymer | 246 | 27677.8 | 2 | Homo sapiens (human) | ||
| 4 | F, H (F, H) | Beta-2-microglobulin | polymer | 100 | 11879.4 | 2 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (human) | |
| 5 | I (A) | 1-(2-deoxy-alpha-D-erythro-pentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione | non-polymer | 256.2 | 1 | Chemie (YC6) PubChem (98561) PubChem (288008) PubChem (16074052) PubChem (44289915) PubChem (58908321) PubChem (92022077) PubChem (57058299) PubChem (142216681) | |||
| 6 | J, M, P, R, T... (A, B, C, F) | GLYCEROL | non-polymer | 92.1 | 7 | Chemie (GOL) PubChem (753) | |||
| 7 | K, L, O, S, U (A, B, C, E) | ACETATE ION | non-polymer | 59.0 | 5 | Chemie (ACT) PubChem (175) | |||
| 8 | N (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) PubChem (312) | |||
| 9 | Q (C) | THYMIDINE | non-polymer | 242.2 | 1 | Chemie (THM) PubChem (1134) PubChem (5789) PubChem (72247) PubChem (159269) PubChem (448456) PubChem (451756) PubChem (453555) PubChem (489518) PubChem (638041) PubChem (7048808) PubChem (44381956) PubChem (46782983) PubChem (3000346) PubChem (5270603) PubChem (57543820) PubChem (57548467) PubChem (58445182) PubChem (59119194) PubChem (68231510) PubChem (68441874) PubChem (68642271) PubChem (68642272) PubChem (121354259) PubChem (142978968) PubChem (144640942) PubChem (163655970) | |||
| 10 | V, Y (E, G) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) PubChem (923) | |||
| 11 | AA, BA, CA, DA, EA... (B, C, D, E, F...) | water | water | 18.0 | 966 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 270 (UniProt: Q95460)
F, H: 1 - 99 (UniProt: P61769)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
| Ser 261 | Cys 283 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 188100.1 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 1519.8 | |
| All* | Total formula weight | 189619.9 |
