9EHS
Structure of a human adenosine A3 receptor complex bound to the covalent antagonist LUF7602
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (H) | BAG2 Anti-BRIL Fab Heavy Chain | polymer | 231 | 24539.3 | 1 | synthetic construct | ||
| 2 | B (K) | elbow nanobody | polymer | 136 | 15071.4 | 1 | synthetic construct | ||
| 3 | C (L) | BAG2 Anti-BRIL Fab Light Chain | polymer | 215 | 23499.1 | 1 | synthetic construct | ||
| 4 | D (R) | Adenosine receptor A3,adenosine A3 receptor fused to BRIL | polymer | 469 | 53118.2 | 1 | UniProt (P0DMS8) Pfam (PF00001) | Homo sapiens (human) | |
| 5 | E (R) | LUF7602 | non-polymer | 517.5 | 1 | Chemie (A1BII) |
Sequence modifications
R: 5 - 208 (UniProt: P0DMS8)
R: 209 - 433 (PDB: 9EHS)
| PDB | External Database | Details |
|---|---|---|
| Asp -35 | - | expression tag |
| Tyr -34 | - | expression tag |
| Lys -33 | - | expression tag |
| Asp -32 | - | expression tag |
| Asp -31 | - | expression tag |
| Asp -30 | - | expression tag |
| Asp -29 | - | expression tag |
| Ala -28 | - | expression tag |
| Met -27 | - | expression tag |
| Gly -26 | - | expression tag |
| Ala -25 | - | expression tag |
| Asn -24 | - | expression tag |
| Phe -23 | - | expression tag |
| Thr -22 | - | expression tag |
| Pro -21 | - | expression tag |
| Val -20 | - | expression tag |
| Asn -19 | - | expression tag |
| Gly -18 | - | expression tag |
| Ser -17 | - | expression tag |
| Ser -16 | - | expression tag |
| Gly -15 | - | expression tag |
| Asn -14 | - | expression tag |
| Gln -13 | - | expression tag |
| Ser -12 | - | expression tag |
| Val -11 | - | expression tag |
| Arg -10 | - | expression tag |
| Leu -9 | - | expression tag |
| Val -8 | - | expression tag |
| Thr -7 | - | expression tag |
| Ser -6 | - | expression tag |
| Ser -5 | - | expression tag |
| Ser -4 | - | expression tag |
| Leu -3 | - | expression tag |
| Glu -2 | - | expression tag |
| Val -1 | - | expression tag |
| Leu 0 | - | expression tag |
| Phe 1 | - | expression tag |
| Gln 2 | - | expression tag |
| Gly 3 | - | expression tag |
| Pro 4 | - | expression tag |
| Arg 97 | Ser 97 | engineered mutation |
| Ala 160 | Asn 160 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 116228.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 517.5 | |
| All* | Total formula weight | 116745.6 |
