9EC0

Structure of the CARMIL dimer bound to Capping Protein

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	F-actin-uncapping protein LRRC16A	polymer	1062	118676.2	2	UniProt (Q5VZK9) Pfam (PF17888) Pfam (PF13516) Pfam (PF16000)	Homo sapiens (human)	CARMIL homolog,Capping protein regulator and myosin 1 linker protein 1,Capping protein,Arp2/3 and myosin-I linker homolog 1,Arp2/3 and myosin-I linker protein 1,Leucine-rich repeat-containing protein 16A
2	C, E (C, E)	F-actin-capping protein subunit alpha-1	polymer	286	32964.7	2	UniProt (P52907) Pfam (PF01267)	Homo sapiens (human)	CapZ alpha-1
3	D, F (D, F)	F-actin-capping protein subunit beta	polymer	276	31258.3	2	UniProt (P47756) Pfam (PF01115)	Homo sapiens (human)	CapZ beta

Sequence modifications

A, B: 1 - 1046 (UniProt: Q5VZK9)

PDB	External Database	Details
Met -7	-	initiating methionine
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
Gly 0	-	expression tag
Trp 1047	-	expression tag
Ser 1048	-	expression tag
His 1049	-	expression tag
Pro 1050	-	expression tag
Gln 1051	-	expression tag
Phe 1052	-	expression tag
Glu 1053	-	expression tag
Lys 1054	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	365798.5
All*	Total formula weight	365798.5

*Water molecules are not included.