Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

9EC0

Structure of the CARMIL dimer bound to Capping Protein

Functional Information from GO Data

Chain	GOid	namespace	contents
C	0003779	molecular_function	actin binding
C	0005515	molecular_function	protein binding
C	0005576	cellular_component	extracellular region
C	0005829	cellular_component	cytosol
C	0005856	cellular_component	cytoskeleton
C	0008290	cellular_component	F-actin capping protein complex
C	0015629	cellular_component	actin cytoskeleton
C	0030036	biological_process	actin cytoskeleton organization
C	0030863	cellular_component	cortical cytoskeleton
C	0034329	biological_process	cell junction assembly
C	0045296	molecular_function	cadherin binding
C	0051015	molecular_function	actin filament binding
C	0051016	biological_process	barbed-end actin filament capping
C	0065003	biological_process	protein-containing complex assembly
C	0070062	cellular_component	extracellular exosome
C	0071203	cellular_component	WASH complex
D	0003779	molecular_function	actin binding
D	0005515	molecular_function	protein binding
D	0005829	cellular_component	cytosol
D	0005856	cellular_component	cytoskeleton
D	0005903	cellular_component	brush border
D	0008290	cellular_component	F-actin capping protein complex
D	0014069	cellular_component	postsynaptic density
D	0015629	cellular_component	actin cytoskeleton
D	0016020	cellular_component	membrane
D	0030017	cellular_component	sarcomere
D	0030027	cellular_component	lamellipodium
D	0030863	cellular_component	cortical cytoskeleton
D	0045296	molecular_function	cadherin binding
D	0051016	biological_process	barbed-end actin filament capping
D	0070062	cellular_component	extracellular exosome
D	0071203	cellular_component	WASH complex
D	0098685	cellular_component	Schaffer collateral - CA1 synapse
D	0098686	cellular_component	hippocampal mossy fiber to CA3 synapse
D	0120212	cellular_component	sperm head-tail coupling apparatus
E	0003779	molecular_function	actin binding
E	0005515	molecular_function	protein binding
E	0005576	cellular_component	extracellular region
E	0005829	cellular_component	cytosol
E	0005856	cellular_component	cytoskeleton
E	0008290	cellular_component	F-actin capping protein complex
E	0015629	cellular_component	actin cytoskeleton
E	0030036	biological_process	actin cytoskeleton organization
E	0030863	cellular_component	cortical cytoskeleton
E	0034329	biological_process	cell junction assembly
E	0045296	molecular_function	cadherin binding
E	0051015	molecular_function	actin filament binding
E	0051016	biological_process	barbed-end actin filament capping
E	0065003	biological_process	protein-containing complex assembly
E	0070062	cellular_component	extracellular exosome
E	0071203	cellular_component	WASH complex
F	0003779	molecular_function	actin binding
F	0005515	molecular_function	protein binding
F	0005829	cellular_component	cytosol
F	0005856	cellular_component	cytoskeleton
F	0005903	cellular_component	brush border
F	0008290	cellular_component	F-actin capping protein complex
F	0014069	cellular_component	postsynaptic density
F	0015629	cellular_component	actin cytoskeleton
F	0016020	cellular_component	membrane
F	0030017	cellular_component	sarcomere
F	0030027	cellular_component	lamellipodium
F	0030863	cellular_component	cortical cytoskeleton
F	0045296	molecular_function	cadherin binding
F	0051016	biological_process	barbed-end actin filament capping
F	0070062	cellular_component	extracellular exosome
F	0071203	cellular_component	WASH complex
F	0098685	cellular_component	Schaffer collateral - CA1 synapse
F	0098686	cellular_component	hippocampal mossy fiber to CA3 synapse
F	0120212	cellular_component	sperm head-tail coupling apparatus

Functional Information from PROSITE/UniProt

site_id	PS00231
Number of Residues	6
Details	F_ACTIN_CAPPING_BETA F-actin capping protein beta subunit signature. CDYNRD

Chain	Residue	Details
D	CYS62-ASP67

site_id	PS00748
Number of Residues	9
Details	F_ACTIN_CAPPING_A_1 F-actin capping protein alpha subunit signature 1. VHYYEDGNV

Chain	Residue	Details
C	VAL196-VAL204

site_id	PS00749
Number of Residues	11
Details	F_ACTIN_CAPPING_A_2 F-actin capping protein alpha subunit signature 2. KaLRRqLPVTR

Chain	Residue	Details
C	LYS256-ARG266

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	48
Details	Repeat: {"description":"LRR 1"}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	46
Details	Repeat: {"description":"LRR 2"}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	46
Details	Repeat: {"description":"LRR 3"}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	54
Details	Repeat: {"description":"LRR 4"}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	54
Details	Repeat: {"description":"LRR 5"}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	48
Details	Repeat: {"description":"LRR 6"}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	50
Details	Repeat: {"description":"LRR 7"}

Chain

Residue

Details

site_id	SWS_FT_FI8
Number of Residues	46
Details	Repeat: {"description":"LRR 8"}

Chain

Residue

Details

site_id	SWS_FT_FI9
Number of Residues	46
Details	Repeat: {"description":"LRR 9"}

Chain

Residue

Details

site_id	SWS_FT_FI10
Number of Residues	48
Details	Repeat: {"description":"LRR 10"}

Chain

Residue

Details

site_id	SWS_FT_FI11
Number of Residues	48
Details	Coiled coil: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI12
Number of Residues	18
Details	Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

site_id	SWS_FT_FI13
Number of Residues	6
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI14
Number of Residues	2
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI15
Number of Residues	6
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)