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9E6Y

Structure of CD112 (Nectin-2) domain 1 bound to CD112R (PVRIG)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(D)
Nectin-2polymer13214399.31UniProt (Q92692)
Pfam (PF07686)
Homo sapiens (human)Herpes virus entry mediator B,Herpesvirus entry mediator B,HveB,Nectin cell adhesion molecule 2,Poliovirus receptor-related protein 2
2B
(A)
Transmembrane protein PVRIGpolymer13313942.71UniProt (Q6DKI7)Homo sapiens (human)CD112 receptor,CD112R,Poliovirus receptor-related immunoglobulin domain-containing protein
3C, D, E, F, G...
(D, A)
1,2-ETHANEDIOLnon-polymer62.111Chemie (EDO)
4I
(A)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.21Chemie (NAG)
5O, P
(D, A)
waterwater18.0105Chemie (HOH)
Sequence modifications
D: 32 - 158 (UniProt: Q92692)
PDBExternal DatabaseDetails
Leu 159-expression tag
Val 160-expression tag
Pro 161-expression tag
Arg 162-expression tag
Leu 163-expression tag
A: 1 - 132 (UniProt: Q6DKI7)
PDBExternal DatabaseDetails
Arg 133-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight28342.0
Non-Polymers*Number of molecules12
Total formula weight904.0
All*Total formula weight29245.9
*Water molecules are not included.

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PDB entries from 2025-06-18

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