9E3M
Cryo-EM structure of the human P2X7 receptor in the apo closed state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, C, B) | P2X purinoceptor 7 | polymer | 595 | 68671.8 | 3 | UniProt (Q99572) Pfam (PF00864) Pfam (PF20478) | Homo sapiens (human) | P2X7,ATP receptor,P2Z receptor,Purinergic receptor |
| 2 | D, E, F, G, H... (D, E, F, G, H...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 6 | In PDB GlyTouCan (G42666HT) | |||
| 3 | J, MA, Y (A, B, C) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 3 | Chemie (GDP) | |||
| 4 | AA, K, L, NA, OA... (C, A, B) | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) | |||
| 5 | BA, CA, M, N, PA... (C, A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 6 | Chemie (NAG) | |||
| 6 | DA, EA, O, P, RA... (C, A, B) | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 6 | Chemie (Y01) | |||
| 7 | FA, GA, HA, IA, JA... (C, A, B) | PALMITIC ACID | non-polymer | 256.4 | 21 | Chemie (PLM) | Homo sapiens | ||
| 8 | X (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 9 | AB, BB, CB (A, C, B) | water | water | 18.0 | 121 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 206015.5 | |
| Branched | Number of molecules | 6 |
| Total formula weight | 2546.4 | |
| Non-Polymers* | Number of molecules | 43 |
| Total formula weight | 11377.6 | |
| All* | Total formula weight | 219939.4 |
