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9E14

Full-length human dynein-1 in phi-like comformation bound to a Lis1 dimer under Nde1-Lis1 condition

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Cytoplasmic dynein 1 heavy chain 1polymer4646533083.32UniProt (Q14204)
Pfam (PF08385)
Pfam (PF03028)
Pfam (PF18198)
Pfam (PF18199)
Pfam (PF08393)
Pfam (PF12774)
Pfam (PF17852)
Pfam (PF12775)
Pfam (PF22597)
Pfam (PF12780)
Pfam (PF12777)
Pfam (PF12781)
Homo sapiens (human)Cytoplasmic dynein heavy chain 1,Dynein heavy chain,cytosolic
2C, D
(C, D)
Cytoplasmic dynein 1 intermediate chain 2polymer63871546.42UniProt (Q13409)
Pfam (PF11540)
Pfam (PF00400)
Homo sapiens (human)Cytoplasmic dynein intermediate chain 2,Dynein intermediate chain 2,cytosolic,DH IC-2
3E, F
(E, F)
Cytoplasmic dynein 1 light intermediate chain 2polymer49254173.22UniProt (O43237)
Pfam (PF05783)
Homo sapiens (human)Dynein light intermediate chain 2,cytosolic,LIC-2,LIC53/55
4G, H
(G, H)
Dynein light chain roadblock-type 1polymer9610934.62UniProt (Q9NP97)
Pfam (PF03259)
Homo sapiens (human)Bithoraxoid-like protein,BLP,Dynein light chain 2A,cytoplasmic,Dynein-associated protein Km23,Roadblock domain-containing protein 1
5I, J
(I, J)
Dynein light chain 1, cytoplasmicpolymer8910381.92UniProt (P63167)
Pfam (PF01221)
Homo sapiens (human)8 kDa dynein light chain,DLC8,Dynein light chain LC8-type 1,Protein inhibitor of neuronal nitric oxide synthase,PIN
6K, L
(K, L)
Dynein light chain Tctex-type 1polymer11312462.02UniProt (P63172)
Pfam (PF03645)
Homo sapiens (human)Protein CW-1,T-complex testis-specific protein 1 homolog
7M, N
(O, P)
Platelet-activating factor acetylhydrolase IB subunit betapolymer41046710.02UniProt (P43034)
Pfam (PF08513)
Pfam (PF00400)
Homo sapiens (human)Lissencephaly-1 protein,LIS-1,PAF acetylhydrolase 45 kDa subunit,PAF-AH 45 kDa subunit,PAF-AH alpha,PAFAH alpha
8O, Q, R, U, W...
(A, B)
ADENOSINE-5'-DIPHOSPHATEnon-polymer427.26Chemie (ADP)
9P, V
(A, B)
ADENOSINE-5'-TRIPHOSPHATEnon-polymer507.22Chemie (ATP)
10S, T, Y, Z
(A, B)
MAGNESIUM IONnon-polymer24.34Chemie (MG)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains14
Total formula weight1478582.6
Non-Polymers*Number of molecules12
Total formula weight3674.8
All*Total formula weight1482257.4
*Water molecules are not included.

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PDB entries from 2026-01-14

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