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9DW7

Dephosphorylated CFTR in 1:2 complex with PKA-C

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C
(K, G)
cAMP-dependent protein kinase catalytic subunit alphapolymer35140677.72UniProt (P00517)
Pfam (PF00069)
Bos taurus (domestic cattle)PKA C-alpha
2B
(A)
Cystic fibrosis transmembrane conductance regulatorpolymer1480168335.51UniProt (P13569)
Pfam (PF00664)
Pfam (PF00005)
Pfam (PF14396)
Homo sapiens (human)CFTR,ATP-binding cassette sub-family C member 7,Channel conductance-controlling ATPase,cAMP-dependent chloride channel
3D
(B)
cystic fibrosis transmembrane conductance regulatorpolymer191635.01Homo sapiens
4E, F
(G)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
5G
(G)
PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTERnon-polymer506.21Chemie (ANP)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight251325.8
Non-Polymers*Number of molecules3
Total formula weight554.8
All*Total formula weight251880.6
*Water molecules are not included.

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PDB entries from 2025-06-11

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