9DRW
Myocilin OLF mutant A427T
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Myocilin | polymer | 277 | 31227.0 | 4 | UniProt (Q99972) Pfam (PF02191) | Homo sapiens (human) | Myocilin 55 kDa subunit,Trabecular meshwork-induced glucocorticoid response protein |
| 2 | E, H, J, L (A, B, C, D) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 3 | F, I, K, M (A, B, C, D) | SODIUM ION | non-polymer | 23.0 | 4 | Chemie (NA) | |||
| 4 | G (B) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | N, O, P, Q (A, B, C, D) | water | water | 18.0 | 759 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 228 - 504 (UniProt: Q99972)
| PDB | External Database | Details |
|---|---|---|
| Thr 427 | Ala 427 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 124908.0 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 344.4 | |
| All* | Total formula weight | 125252.4 |
