9DNN
Insulin receptor in complex with both insulin and de novo designed site-2 binder "S2B".
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Insulin receptor | polymer | 1372 | 155790.5 | 2 | UniProt (P15208) Pfam (PF01030) Pfam (PF00757) Pfam (PF00041) Pfam (PF17870) Pfam (PF07714) | Mus musculus (house mouse) | IR |
| 2 | C, D (C, D) | Insulin | polymer | 110 | 11989.9 | 2 | UniProt (P01308) Pfam (PF00049) | Homo sapiens (human) | |
| 3 | E, F (E, F) | Designed site-2 binder S2B | polymer | 65 | 7552.7 | 2 | synthetic construct |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 350666.2 | |
| All* | Total formula weight | 350666.2 |
