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9DN6

Insulin receptor bound with de novo designed agonist called "RF-405".

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
De novo designed IR agonist RF-405polymer13015288.72synthetic construct
2C, D
(C, D)
Isoform Short of Insulin receptorpolymer1370155329.12UniProt (P06213)
Pfam (PF01030)
Pfam (PF00757)
Pfam (PF00041)
Pfam (PF17870)
Pfam (PF07714)
Homo sapiens (human)IR
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight341235.6
All*Total formula weight341235.6
*Water molecules are not included.

243083

PDB entries from 2025-10-15

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