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9DHH

DHODH in complex with Compound 8

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Dihydroorotate dehydrogenase (quinone), mitochondrialpolymer36939984.71UniProt (Q02127)
Pfam (PF01180)
Homo sapiens (human)DHOdehase,Dihydroorotate oxidase
2B
(A)
FLAVIN MONONUCLEOTIDEnon-polymer456.31Chemie (FMN)
3C
(A)
OROTIC ACIDnon-polymer156.11Chemie (ORO)
4D, F, I, M, Q...
(A)
ACETATE IONnon-polymer59.08Chemie (ACT)
5E
(A)
(3S,7P)-7-[4-ethyl-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-6-fluoro-3-(2-methylphenyl)-1-(propan-2-yl)-2,3-dihydroquinolin-4(1H)-onenon-polymer438.51Chemie (A1A4O)
6G, H, O, P
(A)
SULFATE IONnon-polymer96.14Chemie (SO4)
7J, L
(A)
CHLORIDE IONnon-polymer35.52Chemie (CL)
8K
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
9N
(A)
1,2-ETHANEDIOLnon-polymer62.11Chemie (EDO)
10U
(A)
LAURYL DIMETHYLAMINE-N-OXIDEnon-polymer229.41Chemie (LDA)
11V
(A)
waterwater18.0315Chemie (HOH)
Sequence modifications
A: 30 - 396 (UniProt: Q02127)
PDBExternal DatabaseDetails
Gly 28-expression tag
Ala 29-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight39984.7
Non-Polymers*Number of molecules20
Total formula weight2362.0
All*Total formula weight42346.7
*Water molecules are not included.

237735

PDB entries from 2025-06-18

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