9DGI

Cannabinoid receptor 1-Gi complex with novel ligand

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (R)	Cannabinoid receptor 1	polymer	495	55678.5	1	UniProt (P21554) Pfam (PF00001)	Homo sapiens (human)	CB1,CANN6
2	B (R)	methyl (2R)-2-({(1M)-5-methyl-1-[3-(trifluoromethyl)phenyl]-1H-pyrazole-3-carbonyl}amino)-2-(thiophen-2-yl)propanoate	non-polymer		437.4	1	Chemie (YVF)

Sequence modifications

R: -6 - 472 (UniProt: P21554)

PDB	External Database	Details
Asp -14	-	expression tag
Tyr -13	-	expression tag
Lys -12	-	expression tag
Asp -11	-	expression tag
Asp -10	-	expression tag
Asp -9	-	expression tag
Asp -8	-	expression tag
Ala -7	-	expression tag
Glu 81	-	insertion
Asn 82	-	insertion
Leu 83	-	insertion
Tyr 84	-	insertion
Phe 85	-	insertion
Gln 86	-	insertion
Gly 87	-	insertion
Gly 473	-	expression tag
Ser 474	-	expression tag
His 475	-	expression tag
His 476	-	expression tag
His 477	-	expression tag
His 478	-	expression tag
His 479	-	expression tag
His 480	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	55678.5
Non-Polymers*	Number of molecules	1
	Total formula weight	437.4
All*	Total formula weight	56116.0

*Water molecules are not included.