9DGI
Cannabinoid receptor 1-Gi complex with novel ligand
Functional Information from PROSITE/UniProt
| site_id | PS00237 |
| Number of Residues | 17 |
| Details | G_PROTEIN_RECEP_F1_1 G-protein coupled receptors family 1 signature. ASVgSLFLTAIDRYIsI |
| Chain | Residue | Details |
| R | ALA202-ILE218 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 154 |
| Details | TOPO_DOM: Extracellular => ECO:0000269|PubMed:27768894, ECO:0000269|PubMed:27851727 |
| Chain | Residue | Details |
| R | MET-6-MET109 | |
| R | ASP176-ASN187 | |
| R | ASN256-GLU273 | |
| R | ASP366-THR377 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 25 |
| Details | TRANSMEM: Helical; Name=1 => ECO:0000269|PubMed:27768894, ECO:0000269|PubMed:27851727 |
| Chain | Residue | Details |
| R | LEU117-LEU142 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 146 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000269|PubMed:27768894, ECO:0000269|PubMed:27851727 |
| Chain | Residue | Details |
| R | HIS143-HIS154 | |
| R | ASP213-LYS232 | |
| R | LYS300-THR344 | |
| R | ARG400-LEU472 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=2 => ECO:0000269|PubMed:27768894, ECO:0000269|PubMed:27851727 |
| Chain | Residue | Details |
| R | PHE155-ILE175 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 24 |
| Details | TRANSMEM: Helical; Name=3 => ECO:0000269|PubMed:27768894, ECO:0000269|PubMed:27851727 |
| Chain | Residue | Details |
| R | VAL188-ILE212 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 22 |
| Details | TRANSMEM: Helical; Name=4 => ECO:0000269|PubMed:27768894, ECO:0000269|PubMed:27851727 |
| Chain | Residue | Details |
| R | ALA233-TRP255 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 25 |
| Details | TRANSMEM: Helical; Name=5 => ECO:0000269|PubMed:27768894, ECO:0000269|PubMed:27851727 |
| Chain | Residue | Details |
| R | THR274-TRP299 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=6 => ECO:0000269|PubMed:27768894, ECO:0000269|PubMed:27851727 |
| Chain | Residue | Details |
| R | LEU345-TYR365 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 21 |
| Details | TRANSMEM: Helical; Name=7 => ECO:0000269|PubMed:27768894, ECO:0000269|PubMed:27851727 |
| Chain | Residue | Details |
| R | VAL378-LEU399 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P47746 |
| Chain | Residue | Details |
| R | SER425 | |
| R | SER429 |
| site_id | SWS_FT_FI11 |
| Number of Residues | 1 |
| Details | LIPID: S-palmitoyl cysteine => ECO:0000269|PubMed:21895628 |
| Chain | Residue | Details |
| R | CYS415 |
| site_id | SWS_FT_FI12 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| R | ASN70 | |
| R | ASN76 |
