9DCH
Single-stranded RNA-mediated PRC2 dimer
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (G) | TERRAmut RNA | polymer | 10 | 3258.0 | 1 | Homo sapiens | ||
| 2 | B, H (A, H) | Isoform 2 of Histone-lysine N-methyltransferase EZH2 | polymer | 750 | 86017.9 | 2 | UniProt (Q15910) Pfam (PF11616) Pfam (PF18118) Pfam (PF21358) Pfam (PF18264) Pfam (PF00856) | Homo sapiens (human) | ENX-1,Enhancer of zeste homolog 2,Lysine N-methyltransferase 6 |
| 3 | C, I (B, I) | Polycomb protein SUZ12 | polymer | 727 | 82353.1 | 2 | UniProt (Q15022) Pfam (PF09733) | Homo sapiens (human) | Chromatin precipitated E2F target 9 protein,ChET 9 protein,Joined to JAZF1 protein,Suppressor of zeste 12 protein homolog |
| 4 | D, J (D, K) | RBAP48 | polymer | 425 | 47709.5 | 2 | UniProt (Q09028) Pfam (PF12265) Pfam (PF00400) | Homo sapiens (human) | Chromatin assembly factor 1 subunit C,CAF-1 subunit C,Chromatin assembly factor I p48 subunit,CAF-I 48 kDa subunit,CAF-I p48,Nucleosome-remodeling factor subunit RBAP48,Retinoblastoma-binding protein 4,RBBP-4,Retinoblastoma-binding protein p48 |
| 5 | E, K (F, M) | Zinc finger protein AEBP2 | polymer | 294 | 32881.5 | 2 | UniProt (Q6ZN18) | Homo sapiens (human) | Adipocyte enhancer-binding protein 2,AE-binding protein 2 |
| 6 | F, L (E, L) | Protein Jumonji | polymer | 332 | 36021.4 | 2 | UniProt (Q92833) | Homo sapiens (human) | Jumonji/ARID domain-containing protein 2 |
| 7 | G, M (C, J) | Polycomb protein EED | polymer | 441 | 50267.7 | 2 | UniProt (O75530) Pfam (PF00400) | Homo sapiens (human) | hEED,Embryonic ectoderm development protein,WD protein associating with integrin cytoplasmic tails 1,WAIT-1 |
| 8 | AA, N, O, P, Q... (H, A) | ZINC ION | non-polymer | 65.4 | 14 | Chemie (ZN) |
Sequence modifications
B, I: 13 - 739 (UniProt: Q15022)
| PDB | External Database | Details |
|---|---|---|
| - | Gly 13 | deletion |
| - | Ser 14 | deletion |
| - | Gly 15 | deletion |
| - | Pro 16 | deletion |
| - | Ser 17 | deletion |
| - | Ala 18 | deletion |
| - | Gly 19 | deletion |
| - | Ser 20 | deletion |
| - | Gly 21 | deletion |
| - | Gly 22 | deletion |
| - | Gly 23 | deletion |
| - | Gly 24 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 13 |
| Total formula weight | 673760.1 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 915.7 | |
| All* | Total formula weight | 674675.9 |
