9DBT

Crystal structure of human astrovirus 1 capsid spike bound to human neonatal Fc receptor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E, J (A, F, I, C)	IgG receptor FcRn large subunit p51	polymer	278	30874.7	4	UniProt (P55899) Pfam (PF00129) Pfam (PF07654)	Homo sapiens (human)	FcRn,IgG Fc fragment receptor transporter alpha chain,Neonatal Fc receptor
2	B, D, F, K (B, G, J, D)	Beta-2-microglobulin	polymer	99	11748.2	4	UniProt (P61769) Pfam (PF07654)	Homo sapiens (human)
3	G, H, I, L (H, K, L, E)	Structural protein	polymer	228	25231.7	4	UniProt (Q82452) Pfam (PF12226) UniProt (by SIFTS) (O12792)	Human astrovirus 1	spike

Sequence modifications

A, F, I, C: 24 - 297 (UniProt: P55899)

PDB	External Database	Details
Leu 298	-	expression tag
Val 299	-	expression tag
Pro 300	-	expression tag
Arg 301	-	expression tag

H, K, L, E: 429 - 645 (UniProt: Q82452)

PDB	External Database	Details
Met 428	-	initiating methionine
Ala 646	-	expression tag
Ala 647	-	expression tag
Ala 648	-	expression tag
Glu 649	-	expression tag
Leu 650	-	expression tag
Ala 651	-	expression tag
Leu 652	-	expression tag
Val 653	-	expression tag
Pro 654	-	expression tag
Arg 655	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	271418.1
All*	Total formula weight	271418.1

*Water molecules are not included.