9D9Z
Structure of human UBR4-KCMF1-CaM E3 ligase complex (Silencing Factor of the Integrated stress response, SiFI)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | UBR4 (endogenously FLAG-tagged at the N-terminus),E3 ubiquitin-protein ligase UBR4,E3 ubiquitin-protein ligase UBR4,E3 ubiquitin-protein ligase UBR4 | polymer | 5205 | 577180.9 | 2 | UniProt (Q5T4S7) Pfam (PF19423) Pfam (PF02207) Pfam (PF13764) | Homo sapiens (human) | 600 kDa retinoblastoma protein-associated factor,p600,N-recognin-4,Retinoblastoma-associated factor of 600 kDa,RBAF600 |
| 2 | C, D (C, D) | Calmodulin-1 | polymer | 149 | 16852.5 | 2 | UniProt (P0DP23) Pfam (PF13499) | Homo sapiens (human) | |
| 3 | E, F (E, F) | E3 ubiquitin-protein ligase KCMF1 | polymer | 381 | 41992.3 | 2 | UniProt (Q9P0J7) Pfam (PF00569) Pfam (PF05605) | Homo sapiens (human) | FGF-induced in gastric cancer,Potassium channel modulatory factor,PCMF,ZZ-type zinc finger-containing protein 1 |
| 4 | AA, BA, CA, DA, G... (F, A, B, E) | ZINC ION | non-polymer | 65.4 | 20 | Chemie (ZN) | |||
| 5 | S, T, U, V (C, D) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 1272051.7 | |
| Non-Polymers* | Number of molecules | 24 |
| Total formula weight | 1468.5 | |
| All* | Total formula weight | 1273520.2 |
