9D8Q
Crystal structure of Estrogen Receptor alpha from Melanotaenia fluviatilis bound to estradiol and human SRC2 peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Estrogen receptor | polymer | 250 | 28583.7 | 1 | UniProt (D6N7U3) | Melanotaenia fluviatilis (Murray River rainbowfish) | ER-alpha,Estradiol receptor,Nuclear receptor subfamily 3 group A member 1 |
| 2 | B (B) | Nuclear receptor coactivator 2 | polymer | 13 | 1579.9 | 1 | UniProt (Q15596) | Homo sapiens | NCoA-2,Class E basic helix-loop-helix protein 75,bHLHe75,Transcriptional intermediary factor 2,hTIF2 |
| 3 | C (A) | ESTRADIOL | non-polymer | 272.4 | 1 | Chemie (EST) | |||
| 4 | D (A) | water | water | 18.0 | 8 | Chemie (HOH) |
Sequence modifications
A: 310 - 553 (UniProt: D6N7U3)
| PDB | External Database | Details |
|---|---|---|
| His 304 | - | expression tag |
| His 305 | - | expression tag |
| His 306 | - | expression tag |
| His 307 | - | expression tag |
| His 308 | - | expression tag |
| His 309 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 30163.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 272.4 | |
| All* | Total formula weight | 30435.9 |
