9D5K
Human Adenosine Deaminase Acting on dsRNA (ADAR2-RD) bound to dsRNA containing an expanded cytidine analog at the -1 position of the guide strand
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Isoform 4 of Double-stranded RNA-specific editase 1 | polymer | 487 | 53932.7 | 2 | UniProt (P78563) Pfam (PF00035) Pfam (PF02137) | Homo sapiens (human) | RNA-editing deaminase 1,RNA-editing enzyme 1,dsRNA adenosine deaminase |
| 2 | C (C) | RNA Top Strand | polymer | 32 | 10355.2 | 1 | Homo sapiens | ||
| 3 | D (D) | RNA Bottom Strand | polymer | 32 | 10237.2 | 1 | Homo sapiens | ||
| 4 | E, H (A, B) | INOSITOL HEXAKISPHOSPHATE | non-polymer | 660.0 | 2 | Chemie (IHP) | |||
| 5 | F, I (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 6 | G (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 7 | J, K, L, M (A, B, C, D) | water | water | 18.0 | 34 | Chemie (HOH) |
Sequence modifications
A, B: 215 - 701 (UniProt: P78563)
| PDB | External Database | Details |
|---|---|---|
| Gln 488 | Glu 516 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 128457.7 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1475.2 | |
| All* | Total formula weight | 129932.9 |
