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9D18

Ca2+ bound open-inactivated hSlo1 + beta2N-beta4 channel in detergent-conformation 2 of inactivating domain

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Isoform 5 of Calcium-activated potassium channel subunit alpha-1polymer1056118969.94UniProt (Q12791)
Pfam (PF00520)
Pfam (PF07885)
Pfam (PF22614)
Pfam (PF03493)
Pfam (PF21014)
Homo sapiens (human)BK channel,BKCA alpha,Calcium-activated potassium channel,subfamily M subunit alpha-1,K(VCA)alpha,KCa1.1,Maxi K channel,MaxiK,Slo-alpha,Slo1,Slowpoke homolog,Slo homolog,hSlo
2E, F, G, H
(E, F, G, H)
Large-conductance Ca2+-activated K+ channel beta2 subunit,Calcium-activated potassium channel subunit beta-4polymer23927431.54UniProt (B5BNX0)
UniProt (Q86W47)
Pfam (PF09303)
Pfam (PF03185)
Homo sapiens (human)BK channel subunit beta-4,BKbeta4,Hbeta4,Calcium-activated potassium channel,subfamily M subunit beta-4,Charybdotoxin receptor subunit beta-4,K(VCA)beta-4,Maxi K channel subunit beta-4,Slo-beta-4
3GA, I, PA, V
(C, A, D, B)
MAGNESIUM IONnon-polymer24.34Chemie (MG)
4HA, IA, J, K, QA...
(C, A, D, B)
CALCIUM IONnon-polymer40.18Chemie (CA)
5AB, BB, CA, CB, DA...
(F, G, B, H, C...)
(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphatenon-polymer760.120Chemie (POV)
6AA, BA, KA, LA, M...
(B, C, A, D)
CHOLESTEROLnon-polymer386.711Chemie (CLR)
7FA, O, P, Q
(C, A)
POTASSIUM IONnon-polymer39.14Chemie (K)
Sequence modifications
E, F, G, H: 2 - 44 (UniProt: B5BNX0)
E, F, G, H: 45 - 240 (UniProt: Q86W47)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight585605.9
Non-Polymers*Number of molecules47
Total formula weight20029.0
All*Total formula weight605634.8
*Water molecules are not included.

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PDB entries from 2025-06-25

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