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9D11

Smarca2 Bromodomain in complex with compound 22

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(A, B, C)
Isoform Short of Probable global transcription activator SNF2L2polymer12414434.53UniProt (P51531)
Pfam (PF00439)
Homo sapiens (human)ATP-dependent helicase SMARCA2,BRG1-associated factor 190B,BAF190B,Protein brahma homolog,hBRM,SNF2-alpha,SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2
2D, J, M
(A, B, C)
ZINC IONnon-polymer65.43Chemie (ZN)
3E, K, N
(A, B, C)
(12'S)-4'-chloro-10'-(piperidin-4-yl)-5'H-spiro[cyclohexane-1,7'-indolo[1,2-a]quinazolin]-5'-onenon-polymer419.93Chemie (A1A1O)
4F, H, I
(A)
1,2-ETHANEDIOLnon-polymer62.13Chemie (EDO)
5G, L, O
(A, B, C)
ACETATE IONnon-polymer59.03Chemie (ACT)
6P, Q, R
(A, B, C)
waterwater18.0216Chemie (HOH)
Sequence modifications
A, B, C: 1373 - 1493 (UniProt: P51531)
PDBExternal DatabaseDetails
Ser 1370-expression tag
Asn 1371-expression tag
Ala 1372-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight43303.6
Non-Polymers*Number of molecules12
Total formula weight1819.4
All*Total formula weight45123.0
*Water molecules are not included.

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PDB entries from 2025-07-02

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