9CYR
Crystal structure of D245G mutant human PTP1B (PTPN1) at room temperature (298 K)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Tyrosine-protein phosphatase non-receptor type 1 | polymer | 321 | 37307.6 | 1 | UniProt (P18031) In PDB | Homo sapiens (human) | Protein-tyrosine phosphatase 1B,PTP-1B |
| 2 | A | BETA-MERCAPTOETHANOL | non-polymer | 78.1 | 1 | Chemie (BME) | |||
| 3 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | water | water | 18.0 | 140 | Chemie (HOH) |
Sequence modifications
A: 1 - 321 (UniProt: P18031)
| PDB | External Database | Details |
|---|---|---|
| Gly 245 | Asp 245 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37307.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 102.4 | |
| All* | Total formula weight | 37410.0 |
