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9CYK

SARS-CoV-2 PLpro in complex with inhibitor WEHI-P24

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Papain-like proteasepolymer31835927.72UniProt (P0DTC1)
Pfam (PF08715)
Severe acute respiratory syndrome coronavirus 2Non-structural protein 3, nsp3, PL2-PRO, Papain-like proteinase, PL-PRO
2C, F
(A, B)
{(3R)-1-[(1s,4S)-4-hydroxycyclohexyl]piperidin-3-yl}(6-methoxynaphthalen-2-yl)methanonenon-polymer367.52Chemie (A1A0V)
3D, G
(A, B)
ACETIC ACIDnon-polymer60.12Chemie (ACY)
4E, H
(A, B)
GLYCEROLnon-polymer92.12Chemie (GOL)
5I, J
(A, B)
waterwater18.0344Chemie (HOH)
Sequence modifications
A, B: 1 - 315 (UniProt: P0DTC1)
PDBExternal DatabaseDetails
Ser -2-expression tag
Asn -1-expression tag
Ala 0-expression tag
Ser 111Cys 1674engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight71855.4
Non-Polymers*Number of molecules6
Total formula weight1039.3
All*Total formula weight72894.6
*Water molecules are not included.

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PDB entries from 2025-12-24

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