9CPN
Structural basis of BAK sequestration by MCL-1 and consequences for apoptosis initiation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Induced myeloid leukemia cell differentiation protein Mcl-1 | polymer | 517 | 57281.8 | 4 | synthetic construct | ||
| 2 | E, F, G, H (E, F, G, H) | Bcl-2 homologous antagonist/killer | polymer | 22 | 2453.8 | 4 | UniProt (Q16611) | Homo sapiens (human) | Apoptosis regulator BAK,Bcl-2-like protein 7,Bcl2-L-7 |
| 3 | I, J, K, L (I, J, K, L) | alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | branched | 342.3 | 4 | In PDB BIRD (PRD_900001) GlyTouCan (G07411ON) | |||
| 4 | M, N, O, P, Q... (A, B, C, D, E...) | water | water | 18.0 | 1185 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 238942.4 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 1369.2 | |
| All* | Total formula weight | 240311.6 |
